View source for Projects:ShapeAnalysisOfHippocampus

Shape Analysis of the hippocampus

 Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]

'''Objective''' 

To examine hippocampal shape in patients with schizophrenia and healthy controls.

'''Progress'''

* Initial hippocampal segmentations of healthy control data were successfully processed at UNC (see average asymmetry as examplary analysis in Fig 2.)
* Data has been acquired at 1.5T on 20 patients with schizophrenia and 20 healthy controls at Dartmouth.
* Have begun to apply 3D Slicer for manual segmentation. Additional subject accrual ongoing.

'''Key Investigators'''

* Dartmouth: Andrew Saykin, Tara McHugh, Robert Roth, Laura Flashman
* Harvard: Steve Pieper
* UNC: Martin Styner, Guido Gerig

{|
|+ '''Fig 1. Healthy Asymmetry results'''
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| valign="top" |
<div class="thumb tright"><div style="width: 452px">[[Image:ShapeAnalysisOverviewStatsHippo05.jpg|[[Image:450px-ShapeAnalysisOverviewStatsHippo05.jpg]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:ShapeAnalysisOverviewStatsHippo05.jpg|[[Image:magnify-clip.png|Enlarge]]]]</div></div></div></div>
|}

'''Links'''

* [[Progress_Report:Shape_Analysis|Shape Analysis Progress Report]]
* [[DataRepository#Dartmouth_Structural.2C_Functional.2C_T2_and_DTI_Images|Data Repository for this preliminary analysis]]