View source for Projects:BloodVesselSegmentation

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= Blood Vessel Segmentation =

Atherosclerosis is a systematic disease of the vessel wall that occurs in the aorta, carotid, coronary and peripheral arteries. Atherosclerotic plaques in coronary arteries may cause stenosis (narrowing) or complete occlusion of the arteries and lead to serious results such as heart attacks. Imaging techniques have greatly assisted the diagnoses and treatment procedures of atherosclerosis. Three dimensional imaging such as CTA for coronary arteries is a relatively new approach but has great potentials for detecting and evaluating coronary calcification and stenosis. Fig. 1 (b) shows an example of the 3D reconstruction of coronary arteries and the aorta.

= Description =

[[Image:Fig1yan.PNG | Figure 1]]

A novel image segmentation approach is proposed combining Bayesian pixel classification method and the active surface model in a level set formulation to extract coronary arteries from CT angiography images. Fig. (2) shows the reconstructed coronary arteries from three different patients, and Fig. (3) are sample slices showing the original images and the delineated vessels as cross-sections.

[[Image:Fig2yan.PNG | Figure 2]]

Once the surface of the coronaries are reconstructed, further shape analysis and measurements can be conducted based on it. Fig. (4) shows the results of performing centerline extraction using a hamonic skeletonization technique [3]. The skeletons can then serve as a guide for finding the perpendicular planes to the arteries, and these planes are used to intersect with the vessel in order to measure the local cross-sectional areas, as shown in Fig. (5).

[[Image:Fig3yan.PNG | Figure 3]]

[[Image:Fig4yan.PNG | Figure 4]]

[[Image:Fig5yan.PNG | Figure 5]]

= Key Investigators =

* Georgia Tech:Yan Yang, Allen Tannenbaum 

= Publications =

''In Print''
* [http://www.na-mic.org/Special:Publications?text=Projects%3ABloodVesselSegmentation&submit=Search&words=all&title=checked&keywords=checked&authors=checked&abstract=checked&sponsors=checked&searchbytag=checked| NA-MIC Publications Database]

= Links =

* [[Algorithm:GATech|Georgia Tech Algorithms]]
* [[NA-MIC_Collaborations|NA-MIC Collaborations]]