View source for Projects:DiffusionMeasuresAlongFiberTracts

= Diffusion Measures Along Fiber Tracts =

 Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]

'''Objectives''' 

To quantify changes in diffusion properties along the cingulum bundle for schizophrenics and normal controls.

'''Progress''' 

We improved the diffusion MRI module in slicer to allow for a better fiber selection (based on multiple regions of interest) as well as fiber clustering. We set up a processing pipeline to allow for statistical computations of fiber diffusion properties across the fibers of a fiber bundle and along the bundle itself. Further, we are in the process of developing a continuous representation of fiber bundles (see Figure) to allow for a more geometric computation of bundle diffusion quantities.

[[Image:Cingulum_reseeded_withtrajectories.png|thumb|400px|Cingulum bundle with arclength parameterization.]]

'''Key Investigators'''

* Harvard PNL: Marc Niethammer, Sylvain Bouix, Marek Kubicki, Mark Dreusicke, Martha Shenton
* MIT: CF Westin, Lauren O'Donnell, Raul San Jose

'''Links'''

* [[DBP:Harvard:Collaboration:MITDTI|DBP:Harvard:Collaboration:MITDTI]]
* http://pnl.bwh.harvard.edu/index.html