View source for Projects:BrainActivationDuringContinuousVerbalEncodingAndRecognitionTaskInSchizophrenia

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'''Objective:''' This project employs an event-related auditory verbal episodic memory probe targeting medial temporal and DLPFC circuitry. The task uses a continuous performance format where concrete nouns are presented initially as new items. Words are then repeated after short or long intervals and the participant is required to make a new/old distinction. This design permits analysis of both encoding and recognition processes.

'''Progress:''' To date, data have been collected on 8 patients with schizophrenia and 5 healthy controls. Preliminary analysis on a subset of this data has been completed (see figure below). Sample data is available and more data will become available in year three.

[[Image:NAMIC_AVrecog_prelim_results.jpg|[[Image:NAMIC_AVrecog_prelim_results.jpg|Image:NAMIC_AVrecog_prelim_results.jpg]]]]

'''Year Three Update'''
Data collection and analysis is ongoing.  Updated results are expected at the end of year three.

'''Key Investigators:'''

* Dartmouth: Andrew Saykin, Robert Roth, Laura Flashman, John West, Thomas McAllister
* Harvard: Martha Shenton, Marek Kubicki

'''Links'''

* [[DBP:Marek_Kubicki_visit_Dartmouth_December_20_2005|December 20, 2005: Marek Kubicki visit to Dartmouth]]
* [[DBP:Andy_Saykin_visit_BWH_December_14_2005|December 14, 2005: Andy Saykin and Group visit to Brigham and Women's Hospital]]
* Sample Data: https://portal.nbirn.net/BIRN/cgi-bin/DataGrid/browse.cgi?browseloc=/home/Projects/NAMIC__0003/Files/Dartmouth/HealthyControls6