View source for Integration of Neural Network Algorithms

'''Objective:'''

* Integrate artificial neural network segmentation into the NA-MIC kit for segmentation of upper extremity regions of interest.

'''Progress:'''

* Base algorithm has been developed using the [http://annie.sourceforge.net/ annie neural network library]
* Segmentation algorithm has been applied to segmentation of the phalanx bones on the index finger
**Paper has been published on this initial work 


'''To Do:'''
* Initial evaluation of this technique has been performed for phalanx bones.
* Need to rework ITK neural network libraries to allow the size of the network to be dynamic configured at run time instead of compile time
**There are several issues that neeed to be resolved regarding the Neural network I/O in ITK
**Consider the inclusion of the old ANN code that existed in the BRAINS software

'''Key Investigators:'''

* Iowa: Nicole DeVries, Nicole Grosland, Vincent Magnotta


'''Results'''
{| class="wikitable" border="1" cellpadding="2"
|+ANN Relative Overlap with Manual Rater
|-
! Subject !! Proximal Phalanx !! Middle Phalanx !! Distal Phalanx
|-
| 1 || 0.91 || 0.79 || 0.79
|-
| 2 || 0.91 || 0.88 || 0.84
|-
| 3 || 0.85 || 0.83 || 0.78
|-
| 4 || 0.86 || 0.81 || 0.68
|-
| 5 || 0.84 || 0.78 || 0.72
|-
! Average ||0.87 || 0.82 || 0.76 
|}

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<br>

{| class="wikitable" border="1" cellpadding="2"
|+Average Distance Between ANN Derived Surface and Physical Laser Scanned Surface
|-
! Subject !! Proximal Phalanx (mm) !! Middle Phalanx (mm) !! Distal Phalanx (mm)
|-
| 1 || 0.23||0.12||0.17
|-
| 2 || 0.18||0.16||0.16
|-
| 3 || 0.35||0.27||0.97
|-
| 4 || 0.26||0.17||0.20
|-
! Bone Average ||0.26||0.18||0.38
|}


'''Links:'''
*[http://www.springerlink.com/content/b15376vwx00v5088/ Automated Bony Region Identification Using Artificial Neural Networks: Reliability and Validation Measurements. Esther E. Gassman, Stephanie M. Powell, Nicole A. Kallemeyn, Kiran H. Shivanna, Vincent A. Magnotta, Brian D. Adams, Nicole M. Grosland. Skeletal Radiology]
*[http://www.ccad.uiowa.edu/mimx Musculoskeletal Imaging, Modeling and Experimentation (MIMX)]

'''Figures:'''
[[Image:ANN-Segmentation-Phalanx.jpg |left|thumb|300px|Comparison of the manual and ANN segmentations of the phalanx bones. Manual segmentations are shown in red and automated in blue.]]