Difference between revisions of "Projects/Diffusion/2007 Project Week Slicer3 Tractography Editor"

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<h1>Objective</h1>
 
<h1>Objective</h1>
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We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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Initial development of tractography editing tools.  These include region of interest based selection of fiber bundles in slicer 3, conversion of fiber bundles to voxels, etc.
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<h1>Approach, Plan</h1>
 
<h1>Approach, Plan</h1>
  
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Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below.  The main challenge to this approach is <foo>.
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Build on existing MRML tractography display infrastructure to allow ROI selection of fibers.
  
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Our plan for the project week is to first try out <bar>,...
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Our plan for the project week is to create a CLP module to do region of interest selection of whole brain tractography.
 
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<h1>Progress</h1>
 
<h1>Progress</h1>
  
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Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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Software for the MRML infrastructure and tractography display has been implemented, and is undergoing further improvement. Software for whole brain seeding is being ported to slicer3 as a concurrent programming week project.
  
 
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===References===
 
===References===
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* Fletcher, P.T., Tao, R., Jeong, W.-K., Whitaker, R.T., "A Volumetric Approach to Quantifying Region-to-Region White Matter Connectivity in Diffusion Tensor MRI," to appear Information Processing in Medical Imaging (IPMI) 2007.
 
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* Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., and Gerig, G., "Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis," Medical Image Analysis 10 (2006), 786--798.
 
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* Corouge, I., Fletcher, P.T., Joshi, S., Gilmore J.H., and Gerig, G., Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, Lecture Notes in Computer Science LNCS, James S. Duncan and Guido Gerig, editors, Springer Verlag, Vol. 3749, Oct. 2005, pp. 131 -- 138
 
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* C. Goodlett, I. Corouge, M. Jomier, and G. Gerig, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 

Revision as of 17:07, 21 June 2007

Home < Projects < Diffusion < 2007 Project Week Slicer3 Tractography Editor
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Tract display in Slicer3.


Key Investigators

  • BWH: Raul San Jose, Lauren O'Donnell, Alex Yarmarkovich

Objective

Initial development of tractography editing tools. These include region of interest based selection of fiber bundles in slicer 3, conversion of fiber bundles to voxels, etc.

Approach, Plan

Build on existing MRML tractography display infrastructure to allow ROI selection of fibers.

Our plan for the project week is to create a CLP module to do region of interest selection of whole brain tractography.

Progress

Software for the MRML infrastructure and tractography display has been implemented, and is undergoing further improvement. Software for whole brain seeding is being ported to slicer3 as a concurrent programming week project.



References

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