Difference between revisions of "Projects:ClusteringOfAnatomicallyDistinctFiberTracts"

From NAMIC Wiki
Jump to: navigation, search
Line 3: Line 3:
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]], [[Algorithm:MIT|MIT Algorithms]]
  
'''Objective'''  
+
'''Objectives'''  
  
 
Use fiber clustering in multiple subjects to create a model ("atlas") of tractography clusters. Perform automatic segmentation of novel tractography datasets (brains) by application of this atlas. Also transfer anatomical information via cluster labels in the atlas.
 
Use fiber clustering in multiple subjects to create a model ("atlas") of tractography clusters. Perform automatic segmentation of novel tractography datasets (brains) by application of this atlas. Also transfer anatomical information via cluster labels in the atlas.

Revision as of 14:23, 4 September 2007

Home < Projects:ClusteringOfAnatomicallyDistinctFiberTracts

Clustering Of Anatomically Distinct Fiber Tracts

Back to NA-MIC_Collaborations, MIT Algorithms

Objectives

Use fiber clustering in multiple subjects to create a model ("atlas") of tractography clusters. Perform automatic segmentation of novel tractography datasets (brains) by application of this atlas. Also transfer anatomical information via cluster labels in the atlas.

Progress

Atlas creation and automatic labeling has been performed in high-quality DTI datasets from Susumu Mori. Images showing example segmentation results are below. Work is underway to apply this atlas to segment additional datasets to define regions of interest that may be used in the study of schizophrenia.

Example Results

Selected anatomical regions, automatically labeled using the cluster atlas in 3 subjects.

Subdivisions of the corpus callosum, labeled using the cluster atlas in 3 subjects.

References

Key Investigators

  • MIT: Lauren O'Donnell
  • BWH: Carl-Fredrik Westin, Marek Kubicki, Martha Shenton

Links