Difference between revisions of "NA-MIC/Projects/External Collaboration/Measuring Alcohol and Stress Interaction"
From NAMIC Wiki
| Line 10: | Line 10: | ||
* Wake Forest: Bob Kraft, Jim Daunais | * Wake Forest: Bob Kraft, Jim Daunais | ||
| + | * BWH: Kilian Pohl | ||
* Virginia Tech: Chris Wyatt, Vidya Rajagopalan | * Virginia Tech: Chris Wyatt, Vidya Rajagopalan | ||
| Line 17: | Line 18: | ||
<h1>Objective</h1> | <h1>Objective</h1> | ||
| + | |||
| + | The objectives of this project are to: | ||
| + | # Optimize the EM Brain Classifier in Slicer on MRI images of vervets. | ||
| + | # Segment data from N subjects. | ||
| + | # Optimize GM/WM/CSF segmentation so that calculation of GM/WM volume and ratios between the two states can be automated. | ||
| + | # Optimize hippocampus, putamen and caudate segmentation so that volume comparison between states can be performed. | ||
| Line 24: | Line 31: | ||
<h1>Approach, Plan</h1> | <h1>Approach, Plan</h1> | ||
| − | + | We will use the current implementation of the EM Segmenter in Slicer. Using a manual segmentation as an estimate of ground truth in a single subject, we will optimize the EM segmenter parameters over the classification error and running time. | |
| − | |||
</div> | </div> | ||
| Line 31: | Line 37: | ||
<h1>Progress</h1> | <h1>Progress</h1> | ||
| + | Prior to the project week: | ||
| + | # Study data on 8 subjects at two time points (alcohol naive and post-induction) organized | ||
| + | # GM/WM/CSF atlas will be constructed for the study data. | ||
| + | # An atlas for subcortical structures will be constructed and integrated into the GM/WM/CSF atlas. | ||
| + | |||
Revision as of 13:56, 2 June 2008
Home < NA-MIC < Projects < External Collaboration < Measuring Alcohol and Stress Interaction Return to Project Week Main Page |
Key Investigators
- Wake Forest: Bob Kraft, Jim Daunais
- BWH: Kilian Pohl
- Virginia Tech: Chris Wyatt, Vidya Rajagopalan
Objective
The objectives of this project are to:
- Optimize the EM Brain Classifier in Slicer on MRI images of vervets.
- Segment data from N subjects.
- Optimize GM/WM/CSF segmentation so that calculation of GM/WM volume and ratios between the two states can be automated.
- Optimize hippocampus, putamen and caudate segmentation so that volume comparison between states can be performed.
Approach, Plan
We will use the current implementation of the EM Segmenter in Slicer. Using a manual segmentation as an estimate of ground truth in a single subject, we will optimize the EM segmenter parameters over the classification error and running time.
Progress
Prior to the project week:
- Study data on 8 subjects at two time points (alcohol naive and post-induction) organized
- GM/WM/CSF atlas will be constructed for the study data.
- An atlas for subcortical structures will be constructed and integrated into the GM/WM/CSF atlas.
