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<h1 class="firstHeading">NA-MIC/Projects/Theme/Template</h1>
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<h3 id="siteSub">From NAMIC</h3>
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<td><div class="thumb tright"><div class="thumbinner" style="width:322px;"><a href="/Wiki/index.php/Image:ProjectWeek-2008.png" class="image" title="Return to Project Week Main Page"><img alt="Return to Project Week Main Page" src="/Wiki/images/thumb/8/88/ProjectWeek-2008.png/320px-ProjectWeek-2008.png" width="320" height="241" border="0" class="thumbimage" /></a>  <div class="thumbcaption"><div class="magnify"><a href="/Wiki/index.php/Image:ProjectWeek-2008.png" class="internal" title="Enlarge"><img src="/Wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" /></a></div>Return to <a href="/Wiki/index.php/2008_Summer_Project_Week" title="2008 Summer Project Week">Project Week Main Page</a></div></div></div>
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</td><td><div class="thumb tright"><div class="thumbinner" style="width:322px;"><a href="/Wiki/index.php/Image:GenuFAp.jpg" class="image" title="Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain."><img alt="Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain." src="/Wiki/images/thumb/7/7f/GenuFAp.jpg/320px-GenuFAp.jpg" width="320" height="255" border="0" class="thumbimage" /></a>  <div class="thumbcaption"><div class="magnify"><a href="/Wiki/index.php/Image:GenuFAp.jpg" class="internal" title="Enlarge"><img src="/Wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" /></a></div>Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.</div></div></div>
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</td><td><div class="thumb tright"><div class="thumbinner" style="width:322px;"><a href="/Wiki/index.php/Image:GenuFA.jpg" class="image" title="Regression of FA data; solid line represents the mean and dotted lines the standard deviation."><img alt="Regression of FA data; solid line represents the mean and dotted lines the standard deviation." src="/Wiki/images/thumb/0/0f/GenuFA.jpg/320px-GenuFA.jpg" width="320" height="256" border="0" class="thumbimage" /></a>  <div class="thumbcaption"><div class="magnify"><a href="/Wiki/index.php/Image:GenuFA.jpg" class="internal" title="Enlarge"><img src="/Wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" /></a></div>Regression of FA data; solid line represents the mean and dotted lines the standard deviation.</div></div></div>
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<p><br />
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</p><p><br />
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<a name="Instructions_for_Use_of_this_Template"></a><h3> <span class="mw-headline">Instructions for Use of this Template</span></h3>
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<ol><li>Please create a new wiki page with an appropriate title for your project using the convention NA-MIC/Projects/Theme-Name/Project-Name
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</li><li>Copy the entire text of this page into the page created above
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</li><li>Link the created page into the list of projects for the project event
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</li><li>Delete this section from the created page
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</li><li>Send an email to tkapur at bwh.harvard.edu if you are stuck
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</li></ol>
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<a name="Key_Investigators"></a><h3> <span class="mw-headline">Key Investigators</span></h3>
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<ul><li> UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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</li><li> Utah: Tom Fletcher, Ross Whitaker
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</li></ul>
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<p><br />
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<div style="margin: 20px;">
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<div style="width: 27%; float: left; padding-right: 3%;">
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<a name="Objective"></a><h1> <span class="mw-headline">Objective</span></h1>
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<p>We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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</p><p><br />
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<div style="width: 27%; float: left; padding-right: 3%;">
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<a name="Approach.2C_Plan"></a><h1> <span class="mw-headline">Approach, Plan</span></h1>
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<p>Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below.  The main challenge to this approach is &lt;foo&gt;.
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</p><p>Our plan for the project week is to first try out &lt;bar&gt;,...
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</p>
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</div>
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<div style="width: 40%; float: left;">
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<a name="Progress"></a><h1> <span class="mw-headline">Progress</span></h1>
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<p>Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the <a href="/Wiki/index.php/NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure" class="mw-redirect" title="NA-MIC/Projects/Diffusion Image Analysis/DTI Software and Algorithm Infrastructure">DTI Software Infrastructure</a> project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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</p>
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<p><br style="clear: both;" />
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<p><br />
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<a name="References"></a><h3> <span class="mw-headline">References</span></h3>
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<ul><li> Fletcher, P.T., Tao, R., Jeong, W.-K., Whitaker, R.T., "A Volumetric Approach to Quantifying Region-to-Region White Matter Connectivity in Diffusion Tensor MRI," to appear Information Processing in Medical Imaging (IPMI) 2007.
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</li><li> Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., and Gerig, G., "Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis," Medical Image Analysis 10 (2006), 786--798.
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</li><li> Corouge, I., Fletcher, P.T., Joshi, S., Gilmore J.H., and Gerig, G., Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, Lecture Notes in Computer Science LNCS, James S. Duncan and Guido Gerig, editors, Springer Verlag, Vol. 3749, Oct. 2005, pp. 131 -- 138
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</li><li> C. Goodlett, I. Corouge, M. Jomier, and G. Gerig, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: <a href="http://hdl.handle.net/1926/39" class="external free" title="http://hdl.handle.net/1926/39" rel="nofollow">http://hdl.handle.net/1926/39</a> .
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Revision as of 18:16, 11 June 2008

Home < NA-MIC < Projects < Theme < Carto scar

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<a href="/Wiki/index.php/Image:GenuFAp.jpg" class="image" title="Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain."><img alt="Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain." src="/Wiki/images/thumb/7/7f/GenuFAp.jpg/320px-GenuFAp.jpg" width="320" height="255" border="0" class="thumbimage" /></a>
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Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
<a href="/Wiki/index.php/Image:GenuFA.jpg" class="image" title="Regression of FA data; solid line represents the mean and dotted lines the standard deviation."><img alt="Regression of FA data; solid line represents the mean and dotted lines the standard deviation." src="/Wiki/images/thumb/0/0f/GenuFA.jpg/320px-GenuFA.jpg" width="320" height="256" border="0" class="thumbimage" /></a>
<a href="/Wiki/index.php/Image:GenuFA.jpg" class="internal" title="Enlarge"><img src="/Wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" /></a>
Regression of FA data; solid line represents the mean and dotted lines the standard deviation.



<a name="Instructions_for_Use_of_this_Template"></a>

Instructions for Use of this Template

  1. Please create a new wiki page with an appropriate title for your project using the convention NA-MIC/Projects/Theme-Name/Project-Name
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<a name="Key_Investigators"></a>

Key Investigators

  • UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
  • Utah: Tom Fletcher, Ross Whitaker


<a name="Objective"></a>

Objective

We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.


<a name="Approach.2C_Plan"></a>

Approach, Plan

Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below. The main challenge to this approach is <foo>.

Our plan for the project week is to first try out <bar>,...

<a name="Progress"></a>

Progress

Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the <a href="/Wiki/index.php/NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure" class="mw-redirect" title="NA-MIC/Projects/Diffusion Image Analysis/DTI Software and Algorithm Infrastructure">DTI Software Infrastructure</a> project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.



<a name="References"></a>

References

  • Fletcher, P.T., Tao, R., Jeong, W.-K., Whitaker, R.T., "A Volumetric Approach to Quantifying Region-to-Region White Matter Connectivity in Diffusion Tensor MRI," to appear Information Processing in Medical Imaging (IPMI) 2007.
  • Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., and Gerig, G., "Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis," Medical Image Analysis 10 (2006), 786--798.
  • Corouge, I., Fletcher, P.T., Joshi, S., Gilmore J.H., and Gerig, G., Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, Lecture Notes in Computer Science LNCS, James S. Duncan and Guido Gerig, editors, Springer Verlag, Vol. 3749, Oct. 2005, pp. 131 -- 138
  • C. Goodlett, I. Corouge, M. Jomier, and G. Gerig, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: <a href="http://hdl.handle.net/1926/39" class="external free" title="http://hdl.handle.net/1926/39" rel="nofollow">http://hdl.handle.net/1926/39</a> .


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