Difference between revisions of "NA"

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'''Objective:'''
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'''Objective:''' Develop the next generation biomedical computing application platform using NA-MIC kit software technologies developed in Years 1 & 2 of the NA-MIC project.
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We want to develop new elastic registration methods for brain imaging. The idea is to use optimal transport as the similarity metric underlying the registration procedure. In order to use this technique on 3D manifolds, they must first be warped to the 2D plane using conformal mapping techniques. Additionally, we would like to allow users to be able to specify anatomical landmarks in the form of artificial slits placed in the segmented brain surfaces. During the registration these slits would be forced to register to one another thus guiding the process and producing more accurate results.
 
  
 
'''Progress:'''
 
'''Progress:'''
  
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* This techniques has been implemented for standard 2D images and simple surfaces in [1] and [2] along with application to medical images.
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* Implementation (alpha stage: compile and run) of a base object hierachy with smart pointer, timestamp, factory, tcl wrapping for an independant MRML lib. Allow separation of mrml from vtkmrml, and itkmrml.
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* Code has been developed to accomplish the warping of the brain from a complex 3D surface containing several holes onto the plane.
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* Developed design and initial implementation of module loading facility.
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* Optimal transport has been used to register heart [3] and vessel imagery [4]. These applications required surfaces to be more complex in that they contained holes and other topological challenges such as branches. As a result, they needed more complex flattening procedures.
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* Developed undo/redo facility for MRML data library.
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'''Ongoing:'''
 
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* Further development of algorithms to enable highly complex surfaces with embedded landmark information to be registered using optimal transport.
 
  
 
'''Key Investigators:'''
 
'''Key Investigators:'''
  
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* Steve Haker - Harvard
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* Isomics: Steve Pieper, Alex Yarmarkovich
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* Shawn Lankton - Georgia Tech
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* Kitware: Mathieu Malaterre, Sebastien Barre
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* Lei Zhu - Georgia Tech
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* GE: Bill Lorensen, Jim Miller, Dan Blezek, Xiaodong Tao
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* Allen Tannenbaum - Georgia Tech
 
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* Ron Kikinis - Harvard
 
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'''References:'''
 
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* [1] Haker S, Tannenbaum A, Kikinis R. Mass Preserving Mappings and Image Registration. Proc MICCAI 2001, LCNS 2208; p 120-127
 
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* [2] Haker S, Zhu L, Tannenbaum A, Angenent S. Optimal Mass Transport for Registration and Warping. IJCV, 60(3),225-240,2004; p 225-240
 
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* [3] Zhu L, Haker S, Tannenbaum A. Mass Preserving Registration for Heart MR Images. Proc MICCAI 2005, LCNS 3750; p 147-154
 
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* [4] Zhu L, Haker S, Tannenbaum A. Area-Preserving Mappings for the Visualization of Medical Structures. Proc MICCAI 2003, LCNS 2879; p 277-284
 
  
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<br />'''Links:'''
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'''Links:'''
  
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* [[Algorithm:GATech|GATech Algorithms]]
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* MRML reimplementation proposal: [[User:Mathieu/Slicer|User:Mathieu/Slicer]]
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* [http://www.bme.gatech.edu/groups/bil/ GATech Group Website]
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* [http://www.na-mic.org:8000/websvn/listing.php?repname=Slicer3 Slicer3 websvn]
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* [http://www.na-mic.org:8000/websvn/listing.php?repname=NAMICSandBox&path=%2Ftrunk%2FSlicer30Architecture%2FDataModelManager%2Fmrml%2F libMRML proposal]

Revision as of 13:28, 18 December 2006

Home < NA

Objective: Develop the next generation biomedical computing application platform using NA-MIC kit software technologies developed in Years 1 & 2 of the NA-MIC project.

Progress:

  • Implementation (alpha stage: compile and run) of a base object hierachy with smart pointer, timestamp, factory, tcl wrapping for an independant MRML lib. Allow separation of mrml from vtkmrml, and itkmrml.
  • Developed design and initial implementation of module loading facility.
  • Developed undo/redo facility for MRML data library.

Key Investigators:

  • Isomics: Steve Pieper, Alex Yarmarkovich
  • Kitware: Mathieu Malaterre, Sebastien Barre
  • GE: Bill Lorensen, Jim Miller, Dan Blezek, Xiaodong Tao

Links:

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