Difference between revisions of "Non-rigid MR-CT Image Registration"

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[[Image:nonrigid.png |NON-RIGID MR-CT IMAGE REGISTRATION: This tutorial demonstrates how to perform MR-CT and CT-CT non-rigid registrations. In a cryoablation of liver case, we can see a tumor on pre-operated MRI. However, on intra-operated CT image, the tumor can not be seen though cryoproves can be seen. By using non-rigid MR-CT image registration, we can check the distance between the cryoprobes and tumor as shown the figure.  |500px|thumb|right]]
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= Non-rigid Registration of Pre-procedural MRI and Intra-procedural CT for CT-guided Cryoablation Therapy of Liver Cancer Tutorial=
  
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[[Image:nonrigid-cryo.png |PROCESS OF IMAGE REGISTRATION IN CRYOABLATION OF LIVER CASE: Registration process between MR and CT images in cryoablation of a liver case is shown. (1) A transformation matrix T1 was used to deform the pre-procedure contrast enhanced MR image on to the planning CT image. (2) T2 was used to deform the planning CT image on to the intra procedure CT image with cryoprobes. (3) The matrix T2 was combined with T1 to deform the MR image onto the CT image with cryoprobe. |500px|thumb|right]]  
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==Overview==
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This tutorial demonstrates how to perform a pre-operated contrast enhanced MR image to intra-procedure CT image non-rigid registration.
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The case study is CT-guided liver tumor cryoablation.
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[[Image:nonrigid.png |NON-RIGID MR-CT IMAGE REGISTRATION: As shown in this figure, non-rigid registration can enhance visualization of tumor margin and location. |500px|thumb|right]]
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=== Clinical significants ===
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*Non-rigid registrations desirable to compensate for liver deformation caused by patient positioning, respiratory motion, and interventional manipulation.
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*A multi-modality non-rigid registration method can enhance visualization of tumor margins and location during the planning, targeting, and monitoring phases of CT imaging-guided cryoablation procedure.
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[[Image:registrationStrategy.png |REGISTRATION STRATEGY / ROADMAP:  |500px|thumb|right]]  
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=== Tutorial Topics / Targets ===
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* Slicer Modules Used:
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** N4ITKBiasField Correction
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** Editor
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** BRAINSFitIGT Registration
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* Image Processing Tasks Performed:
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** Intensity non-uniformly correction
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** Mask generation / segmentation
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** Inter-modality non-rigid image registration
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* Image Data Used:
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** Pre-operative abdominal MR with surface coil, showing liver
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** Planning and Intra-operative CT with cryo-probe
  
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= Non-rigid MR-CT Image Registration Tutorial=
 
  
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==Overview==
 
  
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Shape analysis has become of increasing interest to the medical community due to its potential to precisely locate morphological changes between healthy and pathological structures. SPHARM-PDM is a tool that computes point-based models using a parametric boundary description for the computing of Shape analysis.
 
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The point-based models computed with the SPHARM-PDM tool can be used in combination with the also UNC designed statistical tool
 
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[[UNC MANCOVA Tutorial| shapeAnalysisMANCOVA]] to perform quantitative morphological assessment of structural changes at specific locations.
 
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* '''Step by step analysis''': With the ShapeAnalysisModule tutorial,you will learn how to load input volumes, run the module to generate triangulated surfaces with inherent correspondences and visualize them thanks to an intuitive quality control. Indeed,compared with previous versions, the ParticleModule is now part of ShapeAnaysisModule.
 
  
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=== Overview ===
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* This tutorial will go through the following steps (in order):
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* Preprocessing
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** MRI mask generation
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** CT mask generation
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** MRI Bias Field Intensity Correction
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* Registration
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** MRI-CT(#1) non-rigid registration
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** CT(#1)-CT(#2) affine registration
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** Resampling & Fusion
  
 
==Tutorials==
 
==Tutorials==
  
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'''Non-rigid MR-CT Image Registration Module tutorial''' : to perform MR-CT and CT-CT image registration [[Media:ShapeAnalysisModule-Tutorial.ppt|‏ [ppt]]][[Media:ShapeAnalysisModule-Tutorial.pdf|‏ [pdf]]]
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'''Non-rigid Registration of Pre-procedural MRI and Intra-procedural CT for CT-guided Cryoablation Therapy of Liver Cancer Tutorial'''  [[Media:Non-rigid_Registration_of_Pre-procedural_MRI_and_Intra-procedural_CT_for_CT-guided_Cryoablation_Therapy_of_Liver_Cancer_TutorialContestSummer2011.ppt‎|‏ [ppt]]][[Media:Non-rigid_Registration_of_Pre-procedural_MRI_and_Intra-procedural_CT_for_CT-guided_Cryoablation_Therapy_of_Liver_Cancer_TutorialContestSummer2011.pdf|‏ [pdf]]]
  
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==Tutorial materials==
  
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==Tutorial materials==
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'''Material data''':
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*[[Media:Non-rigid_MR_CT_Image_RegistrationTutorialData_TutorialContestSummer2011.tar.gz| Non-rigid_MR_CT_Image_RegistrationTutorialData_TutorialContestSummer2011.tar.gz ]]
  
  
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'''ShapeAnalysisModule data ''':
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==Reference==  
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*[http://www.nitrc.org/docman/index.php?group_id=308&selected_doc_group_id=760&language_id=1#folder Link to NITRC ]
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This method is based on the registration workflow originally developed for prostate MRI registration as follows.
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* or directly here :[[Media:ShapeAnalysisModuleTutorialData_TutorialContestSummer2011.zip|‏ ShapeAnalysisModuleTutorialData_TutorialContestSummer2011.zip]]
 
  
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A. Fedorov, K. Tuncali, F. Fennessy, J. Tokuda, N. Hata, S.W. Wells, R. Kikinis, and C.M. Tempany. Hierarchical Image Registration for Improved Sampling during 3T MRI-guided Transperineal Targeted Prostate Biopsy, ISMRM 2011
  
 
==People==
 
==People==
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Atsushi Yamada, Ph.D (Brigham and Women's Hospital)  
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Atsushi Yamada, Ph.D. (Research Associate, Brigham and Women's Hospital and Harvard Medical School)  
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<br>Dominik S. Meier, Ph.D (Brigham and Women's Hospital)
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<br>Dominik S. Meier, Ph.D. (Assistant Professor, Brigham and Women's Hospital and Harvard Medical School)
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<br>Nobuhiko Hata, Ph.D (Brigham and Women's Hospital)
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<br>Nobuhiko Hata, Ph.D. (Associate Professor, Brigham and Women's Hospital and Harvard Medical School)
  
  
 
==[http://wiki.na-mic.org/Wiki/index.php/Summer_2011_Tutorial_Contest Back to tutorial contest]==
 
==[http://wiki.na-mic.org/Wiki/index.php/Summer_2011_Tutorial_Contest Back to tutorial contest]==

Latest revision as of 21:52, 22 June 2011

Home < Non-rigid MR-CT Image Registration

Non-rigid Registration of Pre-procedural MRI and Intra-procedural CT for CT-guided Cryoablation Therapy of Liver Cancer Tutorial

Overview

This tutorial demonstrates how to perform a pre-operated contrast enhanced MR image to intra-procedure CT image non-rigid registration. The case study is CT-guided liver tumor cryoablation.

NON-RIGID MR-CT IMAGE REGISTRATION: As shown in this figure, non-rigid registration can enhance visualization of tumor margin and location.

Clinical significants

  • Non-rigid registrations desirable to compensate for liver deformation caused by patient positioning, respiratory motion, and interventional manipulation.
  • A multi-modality non-rigid registration method can enhance visualization of tumor margins and location during the planning, targeting, and monitoring phases of CT imaging-guided cryoablation procedure.
REGISTRATION STRATEGY / ROADMAP:

Tutorial Topics / Targets

  • Slicer Modules Used:
    • N4ITKBiasField Correction
    • Editor
    • BRAINSFitIGT Registration
  • Image Processing Tasks Performed:
    • Intensity non-uniformly correction
    • Mask generation / segmentation
    • Inter-modality non-rigid image registration
  • Image Data Used:
    • Pre-operative abdominal MR with surface coil, showing liver
    • Planning and Intra-operative CT with cryo-probe



Overview

  • This tutorial will go through the following steps (in order):
  • Preprocessing
    • MRI mask generation
    • CT mask generation
    • MRI Bias Field Intensity Correction
  • Registration
    • MRI-CT(#1) non-rigid registration
    • CT(#1)-CT(#2) affine registration
    • Resampling & Fusion

Tutorials

Non-rigid Registration of Pre-procedural MRI and Intra-procedural CT for CT-guided Cryoablation Therapy of Liver Cancer Tutorial ‏ [ppt]‏ [pdf]

Tutorial materials

Material data:


Reference

This method is based on the registration workflow originally developed for prostate MRI registration as follows.

A. Fedorov, K. Tuncali, F. Fennessy, J. Tokuda, N. Hata, S.W. Wells, R. Kikinis, and C.M. Tempany. Hierarchical Image Registration for Improved Sampling during 3T MRI-guided Transperineal Targeted Prostate Biopsy, ISMRM 2011

People

Atsushi Yamada, Ph.D. (Research Associate, Brigham and Women's Hospital and Harvard Medical School)
Dominik S. Meier, Ph.D. (Assistant Professor, Brigham and Women's Hospital and Harvard Medical School)
Nobuhiko Hata, Ph.D. (Associate Professor, Brigham and Women's Hospital and Harvard Medical School)


Back to tutorial contest

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