Difference between revisions of "NA-MIC Brains Collaboration"

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Back to [[NA-MIC_External_Collaborations]]
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__NOTOC__
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Back to [[NA-MIC_External_Collaborations|NA-MIC External Collaborations]]
  
 
==Abstract==
 
==Abstract==
This project is not an NCBC collaboration grant, but instead a Continued Development and Maintenance of Software grant. The intent of this application is to update the '''BRAINS''' image analysis software developed at the University of Iowa.  
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This project is not an NCBC collaboration grant, but instead a Continued Development and Maintenance of Software grant. The intent of this application is to update the '''BRAINS''' image analysis software developed at the University of Iowa.
==Grant #==
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1R01NS050568
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==Grant#==
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R01NS050568
  
 
==Key Personnel==
 
==Key Personnel==
The collaborators include Vincent Magnotta, Hans Johnson, Jeremy Bockholt, and Nancy Andreasen.
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*University of Iowa: Vincent Magnotta, PI, Hans Johnson, Jeremy Bockholt, and Nancy Andreasen
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*NA-MIC: Steve Pieper (Isomics)
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==Funding Duration==
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05/15/2007-03/31/2010
  
 
==Projects==
 
==Projects==
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*[[Support for Batch Processing]]
 
*[[Support for Batch Processing]]
 
*[[Visual Review and Verification of Results]]
 
*[[Visual Review and Verification of Results]]
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*[[Build GUI using Slicer3 Interface]]
  
=== Code Refactoring for Cross Platform Support ===
 
*[[Refactor Current Modules using ITK and VTK]]
 
*[[Build GUI using Slicer3 Interface]]
 
*[[Use Python as Scripting Language]]
 
  
=== Validation of Pipeline Using MIND MCIC Sample ===
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=== Validation of Pipeline ===
 
*[[Evaluate MIND MCIC Human Phantom Sample Using Automated Pipeline]]  
 
*[[Evaluate MIND MCIC Human Phantom Sample Using Automated Pipeline]]  
*[[Evaluate Differences between Patients with Schizophrenia and Normal Controls using Automated Pipeline]]
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*[[Evaluate of DTI Reliability Across Sites and Platforms]]
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===Tools Developed===
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Here is a list of tools that are being developed as part of this project. A number of these tools have been contributed to the NITRC website. All of the tools are built upon the Slicer3 execution model and therefore will readily plug-in to Slicer3.
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*[[BRAINSFit]] - Linear fitting of two 3D image sets using a mutual information similarity metric. [http://www.nitrc.org/projects/multimodereg/ NITRC Link]
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*[[BRAINSDemonsWarp]] - Non-linear registration of two image sets. This includes the diffeomorphic demons algorithm along with a number of useful enhancements. [http://www.nitrc.org/projects/brainsdemonwarp/ NITRC Link]
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*[[BRAINSMush]] - Tool to combine T1 and T2 datasets into a composite image. The resulting image is then used to perform brain extraction. [http://www.nitrc.org/projects/brainsmush/ NITRC Link]
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*[[BRAINSCut]] - Automated segmentation of subcortical and cerebellar regions of interest using an artificial neural network. [http://www.nitrc.org/projects/brainscut/ NITRC Link]
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*[[BRAINSTracer]] - Tracing tool that uses thge vtkContourWidget for defining a region of interest manually. [http://www.nitrc.org/projects/brainstracer/ NITRC Link]
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*[[GTRACT]] - Diffusion tensor analysis and Fiber tracking tool. [http://www.nitrc.org/projects/vmagnotta/ NITRC Link]
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*[[BRAINS Automated Pipeline]] - Fully automated image analysis pipeline for generation of volumetric measurements. [http://www.nitrc.org/projects/brains/ NITRC Link]
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=== BRAINS Features ===
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<gallery caption="BRAINS Gallery" widths="200px" heights="200px" perrow="3">
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Image:Surface-Depth.gif|BRAINS Surface showing cortical depth
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Image:Surface-Curvature.gif|BRAINS Surface showing curvature (ie sulcal and gyral labels)
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Image:BRAINS-Tissue-Clasification.gif|BRAINS Continuous Tissue Classification
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Image:ANN-Axial.gif|Automated segmentation of Subcortical nuclei using Neural Networks
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Image:BRAINS-Image-Registration.gif|BRAINS Image Registration using ITK Mutual Information
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Image:FLAIR-Lesion-Labels.gif|Lesion identification with FLAIR, T1 and T2 weighted images
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Image:BRAINS-Talairach-Labels.gif|Talairach lobar labels
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Image:GTRACT-Fiber-Tracking.gif|GTRACT DTI fiber tracking
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</gallery>
  
 
==Publications==
 
==Publications==
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*Powell S., Magnotta V.A., Johnson H., Jammalamadaka V.K., Pierson R., Andreasen N.C. [http://www.na-mic.org/publications/item/view/1755 Registration and machine learning-based automated segmentation of subcortical and cerebellar brain structures.] Neuroimage. 2008 Jan 1;39(1):238-47. PMID: 17904870. PMCID: PMC2253948.
 
==Meetings==
 
==Meetings==
 
==Resource Links==
 
==Resource Links==

Latest revision as of 16:57, 14 December 2016

Home < NA-MIC Brains Collaboration

Back to NA-MIC External Collaborations

Abstract

This project is not an NCBC collaboration grant, but instead a Continued Development and Maintenance of Software grant. The intent of this application is to update the BRAINS image analysis software developed at the University of Iowa.

Grant#

R01NS050568

Key Personnel

  • University of Iowa: Vincent Magnotta, PI, Hans Johnson, Jeremy Bockholt, and Nancy Andreasen
  • NA-MIC: Steve Pieper (Isomics)

Funding Duration

05/15/2007-03/31/2010

Projects

There are three main thrusts of this application as outlined below.

Implement an Automated Brain Analysis Pipeline


Validation of Pipeline

Tools Developed

Here is a list of tools that are being developed as part of this project. A number of these tools have been contributed to the NITRC website. All of the tools are built upon the Slicer3 execution model and therefore will readily plug-in to Slicer3.

  • BRAINSFit - Linear fitting of two 3D image sets using a mutual information similarity metric. NITRC Link
  • BRAINSDemonsWarp - Non-linear registration of two image sets. This includes the diffeomorphic demons algorithm along with a number of useful enhancements. NITRC Link
  • BRAINSMush - Tool to combine T1 and T2 datasets into a composite image. The resulting image is then used to perform brain extraction. NITRC Link
  • BRAINSCut - Automated segmentation of subcortical and cerebellar regions of interest using an artificial neural network. NITRC Link
  • BRAINSTracer - Tracing tool that uses thge vtkContourWidget for defining a region of interest manually. NITRC Link
  • GTRACT - Diffusion tensor analysis and Fiber tracking tool. NITRC Link
  • BRAINS Automated Pipeline - Fully automated image analysis pipeline for generation of volumetric measurements. NITRC Link

BRAINS Features

Publications

Meetings

Resource Links