Difference between revisions of "2008 Summer Project Week:EddyCurrentCorrection"

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<h1>Objective</h1>
 
<h1>Objective</h1>
We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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The objective is to create software for correcting head motion and eddy current artifacts in DWIs.
 
 
  
 
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<h1>Approach, Plan</h1>
 
<h1>Approach, Plan</h1>
 
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We implemented the diffusion weighted image (DWI) registration model from the paper of G.K.Rohde et al. Patient head motion and eddy currents distortion cause artifacts in maps of diffusion parameters computed from DWI. This model corrects these two distortions at the same time including brightness correction.
Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below. The main challenge to this approach is <foo>.
 
 
 
Our plan for the project week is to first try out <bar>,...
 
 
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<h1>Progress</h1>
 
<h1>Progress</h1>
 
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* We have implemented a simple command line module. We plan to add the gradient rotation, sinc interpolation and to make an easy to use Slicer module.
Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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* An ITK module has been written takes a nrrd dwi in and gives a nrrd dwi back.
 
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* Will follow up with testing and make it a slicer3 command line module
 
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===References===
 
===References===
 
[1] G.K.Rohde, A.S.Barnett, P.J.Basser, S.Marenco, and C.Pierpaoli, et al., "Comprehensive Approach for Correction of Motion and Distortion in Diffusion-Weighted MRI," Magnetic Resonance in Medicine 51:103-114(2004)
 
[1] G.K.Rohde, A.S.Barnett, P.J.Basser, S.Marenco, and C.Pierpaoli, et al., "Comprehensive Approach for Correction of Motion and Distortion in Diffusion-Weighted MRI," Magnetic Resonance in Medicine 51:103-114(2004)

Latest revision as of 14:04, 27 June 2008

Home < 2008 Summer Project Week:EddyCurrentCorrection
Coronal slice from a unregisted DTI (left). The same slice after applying the registration model (right).




Key Investigators

  • Utah: Ran Tao, Tom Fletcher, Ross Whitaker
  • BWH: Sylvain Bouix
  • GE: Xiaodong Tao


Objective

The objective is to create software for correcting head motion and eddy current artifacts in DWIs.

Approach, Plan

We implemented the diffusion weighted image (DWI) registration model from the paper of G.K.Rohde et al. Patient head motion and eddy currents distortion cause artifacts in maps of diffusion parameters computed from DWI. This model corrects these two distortions at the same time including brightness correction.

Progress

  • We have implemented a simple command line module. We plan to add the gradient rotation, sinc interpolation and to make an easy to use Slicer module.
  • An ITK module has been written takes a nrrd dwi in and gives a nrrd dwi back.
  • Will follow up with testing and make it a slicer3 command line module


References

[1] G.K.Rohde, A.S.Barnett, P.J.Basser, S.Marenco, and C.Pierpaoli, et al., "Comprehensive Approach for Correction of Motion and Distortion in Diffusion-Weighted MRI," Magnetic Resonance in Medicine 51:103-114(2004)