Difference between revisions of "2008 Summer Project Week:DWI-DTI PrepTools"

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We are developing a tool for preparing diffusion weighted and diffusion tensor image data.
 
We are developing a tool for preparing diffusion weighted and diffusion tensor image data.
  
Details of the tool functionality were discussed thus far between UNC and Utah. The discussions have been summarized in [[2008_Core_1_UNC_Utah_DTI|it's event page]]:
+
Details of the tool functionality were discussed [[2008_Core_1_UNC_Utah_DTI|between UNC and Utah]]:
  
* The tool will allow a "protocol" based execution via parameter files. The parameter files contain all the settings/preferences/options and this file can be created using the tool's GUI
+
* "Protocol" based execution  
* This tool will handle the conversion of DICOM data to volumetric image formats (NRRD) using existing ITK-NAMIC classes
+
** Parameter files contain all settings
* The tool performs automated quality control, corrects data if possible, possibly rejects parts of the data, and provides a reporting facility. The following functionalities will be supported:
+
* Handles conversion of DICOM data to volumetric formats (NRRD)
** Motion correction (using Utah modules)
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* Automated quality control, corrects/rejects, provides reporting facility.  
** Eddy current correction (using Utah modules)
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* Motion correction  
** Interpolation of data, e.g. to upinterpolate to isotropic data
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* Eddy current correction  
** Quality Control
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* Interpolation of data
*** Rejection of interslice brightness, white or black slice at level of direction images
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* Rejection of interslice brightness
*** Local plausibility check with reconstructed DTI. Reject direction image if implausable results
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* Local plausibility check with reconstructed DTI
*** FA/MD histogram comparison with atlas  
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* FA/MD histogram comparison with atlas  
*** Local dot product of principal direction with atlas,
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* Local dot product of principal direction with atlas
*** Full brain tracking to check for possible flips, permutations of direction axes  
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* Full brain tracking for flips/permutations of axes  
*** Focus QC on white matter only, segment WM from baseline image via Slicer-itkEMS implementation
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* Focus QC on white matter only
* Furthermore, DTI data is generated (using Slicer/UNC modules), as well as directly derived images, such as FA/MD etc
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* DTI data, as well as FA/MD  
* Fltk vs KWWidget: Is Fltk appropriate here?
 
  
  
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<h1>Progress</h1>
 
<h1>Progress</h1>
 
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During the 2008 project week:
 +
* We met with Xiaodong Tao and talked with him the Dicom to nrrd transform and DTI estimation. We will incorporate his Dicom/nrrd format transform work into our pipeline.
 +
* We met with Casey Goodlett and learned atlas based DTI analysis. Our DWI/DTI preparing tools will run the QC process based on a DTI atlas.
 +
* We met Ran Tao from Universith of Utha. We will use their motion/eddy current distortion correction program in our QC pipeline. We also found that extra checking should be performed on the output of this correction procedure, for some of the inferior and superior slices may contain only pieces of brain structures due to the transform during correction.
  
 
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===References===
 
===References===

Latest revision as of 14:02, 27 June 2008

Home < 2008 Summer Project Week:DWI-DTI PrepTools




Key Investigators

  • UNC: Heather Cody Hazlett, Martin Styner, Zhexing Liu
  • Utah: Casey Goodlett, Guido Gerig, Tom Fletcher


Objective

We are developing a tool for preparing diffusion weighted and diffusion tensor image data.

Details of the tool functionality were discussed between UNC and Utah:

  • "Protocol" based execution
    • Parameter files contain all settings
  • Handles conversion of DICOM data to volumetric formats (NRRD)
  • Automated quality control, corrects/rejects, provides reporting facility.
  • Motion correction
  • Eddy current correction
  • Interpolation of data
  • Rejection of interslice brightness
  • Local plausibility check with reconstructed DTI
  • FA/MD histogram comparison with atlas
  • Local dot product of principal direction with atlas
  • Full brain tracking for flips/permutations of axes
  • Focus QC on white matter only
  • DTI data, as well as FA/MD


Approach, Plan

The tool will allow a "protocol" based execution via parameter files. The parameter files contain all the settings/preferences/options and this file can be created using the tool's GUI. This tool will handle the conversion of DICOM data to volumetric image formats (NRRD), perform automated quality control, correct data if possible, possibly reject parts of the data and provide a reporting facility.

Progress

During the 2008 project week:

  • We met with Xiaodong Tao and talked with him the Dicom to nrrd transform and DTI estimation. We will incorporate his Dicom/nrrd format transform work into our pipeline.
  • We met with Casey Goodlett and learned atlas based DTI analysis. Our DWI/DTI preparing tools will run the QC process based on a DTI atlas.
  • We met Ran Tao from Universith of Utha. We will use their motion/eddy current distortion correction program in our QC pipeline. We also found that extra checking should be performed on the output of this correction procedure, for some of the inferior and superior slices may contain only pieces of brain structures due to the transform during correction.


References