2011 Scientific Progress Report

Report Outline

Highlights (Will Schroeder, Missing)

• Advanced algorithms

• NA-MIC Kit

• Table of Downloads

• Dissemination: SECTION PROVIDED BY TINA

Impact (Jim Miller, Submitted to Ann)

• Impact within the Center

• Impact within NIH-Funded Research

• National and International Impact

DBPs

Head and Neck Cancer, Greg Sharp

Submitted.

Traumatic Brain Injury, Jack Van Horn

Submitted.

CS Core

Algorithms (Ross)

• Statistical Models of Anatomy and Pathology, Polina Golland

• Geometric Correspondence, Guido Gerig

• User Interactive Tools for Segmentation, Allen Tannenbaum

• Longitudinal and Time Series Analysis, Martin Styner

Publications

1. Wang Y., Gupta A., Liu Z., Zhang H., Escolar M.L., Gilmore J.H., Gouttard S., Fillard P., Maltbie E., Gerig G., Styner M. DTI Registration in Atlas Based Fiber Analysis of Infantile Krabbe Disease. Neuroimage. 2011 Apr 15;55(4):1577-86. PMID: 21256236. PMCID: PMC3062693.

2. Pohl K.M., Konukoglu E., Novellas S., Ayache N., Fedorov A., Talos I-F., Golby A., Wells III W.M., Kikinis R., Black P.M. A New Metric for Detecting Change in Slowly Evolving Brain Tumors: Validation in Meningioma Patients. Neurosurgery. 2011 Mar;68(1 Suppl Operative):225-33. PMID: 21206318.

3. Leritz E.C., Salat D.H., Williams V.J., Schnyer D.M., Rudolph J.L., Lipsitz L., Fischl B., McGlinchey R.E., Milberg W.P. Thickness of the Human Cerebral Cortex is Associated with Metrics of Cerebrovascular Health in a Normative Sample of Community Dwelling Older Adults. Neuroimage. 2011 Feb 14;54(4):2659-71. PMID: 21035552. PMCID: PMC3026290.

4. Salat D.H., Chen J.J., Van der Kouwe A.J.W., Greve D.N., Fischl B., Rosas H.D. Hippocampal Degeneration is Associated with Temporal and Limbic Gray Matter/White Matter Tissue Contrast in Alzheimer's Disease. Neuroimage. 2011 Feb 1;54(3):1795-802. PMID: 20965261. PMCID: PMC3021138.

5. Wang X., Grimson W.E.L., Westin C-F. Tractography Segmentation using a Hierarchical Dirichlet Processes Mixture Model. Neuroimage. 2011 Jan 1;54(1):290-302. PMID: 20678578. PMCID: PMC2962770.

6. Oguro S., Tuncali K., Elhawary H., Morrison P.R., Hata N., Silverman S.G. Image Registration of Pre-procedural MRI and Intra-procedural CT Images to Aid CT-guided Percutaneous Cryoablation of Renal Tumors. Int J Comput Assist Radiol Surg. 2011 Jan;6(1):111-7. PMID: 20499194. PMCID: PMC3050046.

7. Mohan V., Sundaramoorthi G., Tannenbaum A. Tubular Surface Segmentation for Extracting Anatomical Structures from Medical Imagery. IEEE Trans Med Imaging. 2010 Dec;29(12):1945-58. PMID: 21118754.

8. Langs G., Golland P., Tie Y., Rigolo L., Golby A.J. Functional Geometry Alignment and Localization of Brain Areas. Proceedings of the 24^th Annual Conference on Neural Information Processing Systems 2010; 1:1225-1233.

9. Shenton M.E., Whitford T.J., Kubicki M. Structural Neuroimaging in Schizophrenia: From Methods to Insights to Treatments. Dialogues Clin Neurosci. 2010;12(3):317-32. PMID: 20954428.

10. Nho K., Shen L., Kim S., Risacher S.L., West J.D., Foroud T., Jack C.R., Weiner M.W., Saykin A.J. Automatic Prediction of Conversion from Mild Cognitive Impairment to Probable Alzheimer's Disease using Structural Magnetic Resonance Imaging. AMIA Annu Symp Proc. 2010 Nov 13;2010:542-6. PMID: 21347037. PMCID: PMC3041374.

11. Kikinis Z., Fallon J.H., Niznikiewicz M., Nestor P., Davidson C., Bobrow L., Pelavin P.E., Fischl B., Yendiki A., McCarley R.W., Kikinis R., Kubicki M., Shenton M.E. Gray Matter Volume Reduction in Rostral Middle Frontal Gyrus in Patients with Chronic Schizophrenia. Schizophr Res. 2010 Nov;123(2-3):153-9. PMID: 20822884. PMCID: PMC2975427.

12. Kremen W.S., O'Brien R.C., Panizzon M.S., Prom-Wormley E., Eaves L.J., Eisen S.A., Eyler L.T., Hauger R.L., Fennema-Notestine C., Fischl B., Grant M.D., Hellhammer D.H., Jak A.J., Jacobson K.C., Jernigan T.L., Lupien S.J., Lyons M.J., Mendoza S.P., Neale M.C., Seidman L.J., Thermenos H.W., Tsuang M.T., Dale A.M., Franz C.E. Salivary Cortisol and Prefrontal Cortical Thickness in Middle-aged Men: A Twin Study. Neuroimage. 2010 Nov 15;53(3):1093-102. PMID: 20156572.

13. Elhawary H., Oguro S., Tuncali K., Morrison P.R., Tatli S., Shyn P.B., Silverman S.G., Hata N. Multimodality Non-rigid Image Registration for Planning, Targeting and Monitoring during CT-guided Percutaneous Liver Tumor Cryoablation. Acad Radiol. 2010 Nov;17(11):1334-44. PMID: 20817574. PMCID: PMC2952665.

14. Gerber S., Bremer P-T., Pascucci V., Whitaker R. Visual Exploration of High Dimensional Scalar Functions. IEEE Trans Vis Comput Graph. 2010 Nov-Dec;16(6):1271-80. PMID: 20975167.

15. Ghosh S.S., Kakunoori S., Augustinack J., Nieto-Castanon A., Kovelman I., Gaab N., Christodoulou J.A., Triantafyllou C., Gabrieli J.D.E., Fischl B. Evaluating the Validity of Volume-based and Surface-based Brain Image Registration for Developmental Cognitive Neuroscience Studies in Children 4 to 11 Years of Age. Neuroimage. 2010 Oct 15;53(1):85-93. PMID: 20621657. PMCID: PMC2914629.

16. Destrieux C., Fischl B., Dale A., Halgren E. Automatic Parcellation of Human Cortical Gyri and Sulci using Standard Anatomical Nomenclature. Neuroimage. 2010 Oct 15;53(1):1-15. PMID: 20547229. PMCID: PMC2937159.

17. Riklin-Raviv T., Van Leemput K., Menze B.H., Wells III W.M., Golland P. Segmentation of Image Ensembles via Latent Atlases. Med Image Anal. 2010 Oct;14(5):654-65. PMID: 20580305. PMCID: PMC2932709.

18. Sabuncu M.R., Yeo B.T.T., Van Leemput K., Fischl B., Golland P. A Generative Model for Image Segmentation Based on Label Fusion. IEEE Trans Med Imaging. 2010 Oct;29(10):1714-29. PMID: 20562040.

19. Gerber S., Tasdizen T., Thomas Fletcher P., Joshi S., Whitaker R. Manifold Modeling for Brain Population Analysis. Med Image Anal. 2010 Oct;14(5):643-53. PMID: 20579930. PMCID: PMC3020141.

20. Gao Y., Sandhu R., Fichtinger G., Tannenbaum A.R. A Coupled Global Registration and Segmentation Framework with Application to Magnetic Resonance Prostate Imagery. IEEE Trans Med Imaging. 2010 Oct;29(10):1781-94. PMID: 20529727. PMCID: PMC2988404.

EAB REPORT (Lorensen)

• Bill expects to complete this by Friday, April, 8, 2011.