Difference between revisions of "2011 Summer Project Week White Matter Laterality"
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* Harvard Medical School: Lauren O'Donnell | * Harvard Medical School: Lauren O'Donnell | ||
* Kitware: JC (Thanks for help on how to integrate as a Slicer4 module/extension) | * Kitware: JC (Thanks for help on how to integrate as a Slicer4 module/extension) | ||
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#:Slicer-ification is goal for this week | #:Slicer-ification is goal for this week | ||
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#:Another goal: learn how to make an extension module | #:Another goal: learn how to make an extension module | ||
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#:Another goal: can this module use testing framework | #:Another goal: can this module use testing framework | ||
Latest revision as of 14:58, 24 June 2011
Home < 2011 Summer Project Week White Matter Laterality
before automatic midsagittal alignment
after automatic midsagittal alignment. Note increased symmetry (green laterality indices, near 0)
White Matter Laterality/Asymmetry Measurement
Key Investigators
- Harvard Medical School: Lauren O'Donnell
- Kitware: JC (Thanks for help on how to integrate as a Slicer4 module/extension)
- Harvard Medical School: Sandy Wells (Thanks for helpful discussions on angle representation and objective functions for registration)
Objective
- Fast computation of white matter
- fiber tract laterality indices
- in python and ... Slicer4
Approach, Plan
- So far have preliminary code running in python/vtk
- Slicer-ification is goal for this week
- Another goal: learn how to make an extension module
- Another goal: can this module use testing framework
Progress
- Project is now organized as a python package
- Command line script written to run on large groups
- Initial testing on R/L handedness group data showed significant differences
- Preprocessing and midsagittal alignment have been implemented
References
The fiber laterality histogram: A new way to measure white matter asymmetry. Lauren J. O'Donnell, Carl-Fredrik Westin, Isaiah Norton, Stephen Whalen, Laura Rigolo, Ruth Propper, and Alexandra J. Golby Med Image Comput Comput Assist Interv. 2010; 13(Pt 2): 225-232
Delivery Mechanism
This work will be delivered to the NAMIC Kit as a
- NITRIC distribution
- Slicer Module
- Built-in:
- Extension -- commandline:
- Extension -- loadable:
