Difference between revisions of "RT dose comparison tool for Slicer"

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__NOTOC__
 
__NOTOC__
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<gallery>
 
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Image:PW-SLC2012.png|[[2012_Winter_Project_Week#Projects|Projects List]]
 
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</gallery>
 
  
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[[Image:namic-isodose.png|300px|Isodose lines in Slicer 3]]
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[[Image:panel.png|300px|Slicer 3 GUI panel]]
  
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[[Image:isodose1.png|600px|Isodose lines in Slicer 3]]
  
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[[Image:namic-gamma.png|300px|Image of gamma index in Slicer 3]]
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[[Image:gamma_label.png|600px|Image of gamma index in Slicer 3]]
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==Instructions for Use of this Template==
 
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#Please create a new wiki page with an appropriate title for your project using the convention 2012_Winter_Project_Week:<Project Name>
 
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#Copy the entire text of this page into the page created above
 
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#Link the created page into the list of projects for the project event
 
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#Delete this section from the created page
 
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#Send an email to tkapur at bwh.harvard.edu if you are stuck
 
  
 
==Key Investigators==
 
==Key Investigators==
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* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* MGH: Nadya Shusharina, Greg Sharp
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* Utah: Tom Fletcher, Ross Whitaker
 
  
 
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<div style="margin: 20px;">
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<h3>Objective</h3>
 
<h3>Objective</h3>
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We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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We are developing a tool for analyzing dose distributions. The goal is to be able to make quantitative evaluation of different dose distributions in association with RT structures of interest.
  
  
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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
  
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Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below. The main challenge to this approach is <foo>.
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Our approach for analyzing dose distributions is to create multiple modes of dose difference quantification that complement each other. Simultaneous evaluation of isodoses, dose-difference and distance-to-agreemnet distributions will be used to determine dissimilarities of two dose images.  
  
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Our plan for the project week is to first try out <bar>,...
 
  
 
</div>
 
</div>
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<div style="width: 40%; float: left;">
 
<div style="width: 40%; float: left;">
  
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<h3>Progress</h3>
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<h3>Progress</h3>We created Plastimatch based command line module for Slicer3 titled "Dose comparison" that allows us to create and display isodoses, image dose-difference and distance-to-agreement distributions according to user's needs. Better representation of isodose labelmap is needed to be able to create overlaping isodose surfaces.
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Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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==Delivery Mechanism==
 
==Delivery Mechanism==
  
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This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)
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This work will be delivered to the NA-MIC Kit as a  
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Extension -- commandline
  
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#ITK Module
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==References==
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#Slicer Module
 
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##Built-in
 
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##Extension -- commandline
 
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##Extension -- loadable
 
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#Other (Please specify)
 
  
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==References==
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* [http://plastimatch.org/ Plastimatch]
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*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
 
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* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
 
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* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
 
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* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 
  
 
</div>
 
</div>

Latest revision as of 22:50, 12 January 2012

Home < RT dose comparison tool for Slicer


Slicer 3 GUI panel

Isodose lines in Slicer 3

Image of gamma index in Slicer 3

Key Investigators

  • MGH: Nadya Shusharina, Greg Sharp

Objective

We are developing a tool for analyzing dose distributions. The goal is to be able to make quantitative evaluation of different dose distributions in association with RT structures of interest.




Approach, Plan

Our approach for analyzing dose distributions is to create multiple modes of dose difference quantification that complement each other. Simultaneous evaluation of isodoses, dose-difference and distance-to-agreemnet distributions will be used to determine dissimilarities of two dose images.


Progress

We created Plastimatch based command line module for Slicer3 titled "Dose comparison" that allows us to create and display isodoses, image dose-difference and distance-to-agreement distributions according to user's needs. Better representation of isodose labelmap is needed to be able to create overlaping isodose surfaces.



Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a Extension -- commandline

References

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