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  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
 
  Back to [[NA-MIC_Collaborations|NA-MIC_Collaborations]]
  
'''Objectives''' The primary dissemination goal in the second year of NA-MIC was to focus on outreach to the broader research community
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'''Objective:''' We are developing a software infrastructure within ITK for DTI analysis. This includes algorithms for statistical analysis of diffusion tensors, fiber tractography, image filtering and registration.
  
'''Progress''' This outreach goal was accomplished using several mechanisms. In addition to the training events reported by the Training core, three workshops and two birds-of-a-feather meetings were held in collaboration with the Service core. Three invited talks were presented about NA-MIC, and the wiki-based collaborative web presence was also approximately doubled in this time.
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'''Progress:'''
  
'''Key Investigators'''
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* ''Geometric tools for diffusion tensor analysis.'' We have built a framework for geometric computations on tensors. This includes vector space operations on tensors as well as nonlinear operations that preserve the positive eigenvalues of the tensors. These geometric methods are the foundation for many of the tools below.
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* ''Statistical tools for diffusion tensor analysis.'' We have implemented methods for computing averages, covariances, and statistical group comparisons of diffusion tensor data.
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* ''Fiber tractography.'' We have developed software for tracking and viewing white matter fiber tracts. This tool has been combined with the statistical methods above for analysis and group comparisons of diffusion tensor data along white matter tracts.
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* ''Diffusion Tensor image filtering.'' We are building a framework within ITK for filtering diffusion tensor images. This includes several methods from the literature and both methods that filter estimated tensor fields and those that filter the original diffusion weighted data.
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* ''Diffusion Tensor image registration.'' We are building a framework within ITK for registration of diffusion tensor images. This requires image match metrics, interpolation of tensor images, and tensor image transformations.
  
* Tina Kapur, Epiphany Medical
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''Reference:'' Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., Gerig, G. Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, presented at MICCAI 2005.
* Steve Pieper, Isomics
 
* Ron Kikinis, Harvard
 
* Luis Ibanez, Kitware
 
* Bill Lorensen, GE Research
 
  
'''Links'''
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'''Key Investigators:'''
  
* [[Dissemination:Progress_Report:2006|Dissemination:Progress Report:2006]]
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* Utah: Tom Fletcher, Ross Whitaker
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* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* GE: Jim Miller
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'''Links:'''
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* [[Progress_Report:Diffusion_Tensor_Statistics|Diffusion Tensor Statistics Progress Report]]
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'''Representative Image and Descriptive Caption:'''
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<div class="thumb tleft"><div style="width: 822px">[[Image:Tensor_interp.jpg|[[Image:Tensor_interp.jpg|Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.]]]]<div class="thumbcaption"><div class="magnify" style="float: right">[[Image:Tensor_interp.jpg|[[Image:magnify-clip.png|Enlarge]]]]</div>Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.</div></div></div>

Revision as of 14:04, 18 December 2006

Home < NA
Back to NA-MIC_Collaborations

Objective: We are developing a software infrastructure within ITK for DTI analysis. This includes algorithms for statistical analysis of diffusion tensors, fiber tractography, image filtering and registration.

Progress:

  • Geometric tools for diffusion tensor analysis. We have built a framework for geometric computations on tensors. This includes vector space operations on tensors as well as nonlinear operations that preserve the positive eigenvalues of the tensors. These geometric methods are the foundation for many of the tools below.
  • Statistical tools for diffusion tensor analysis. We have implemented methods for computing averages, covariances, and statistical group comparisons of diffusion tensor data.
  • Fiber tractography. We have developed software for tracking and viewing white matter fiber tracts. This tool has been combined with the statistical methods above for analysis and group comparisons of diffusion tensor data along white matter tracts.
  • Diffusion Tensor image filtering. We are building a framework within ITK for filtering diffusion tensor images. This includes several methods from the literature and both methods that filter estimated tensor fields and those that filter the original diffusion weighted data.
  • Diffusion Tensor image registration. We are building a framework within ITK for registration of diffusion tensor images. This requires image match metrics, interpolation of tensor images, and tensor image transformations.

Reference: Corouge, I., Fletcher, P.T., Joshi, S., Gilmore, J.H., Gerig, G. Fiber Tract-Oriented Statistics for Quantitative Diffusion Tensor MRI Analysis, presented at MICCAI 2005.

Key Investigators:

  • Utah: Tom Fletcher, Ross Whitaker
  • UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
  • GE: Jim Miller

Links:

Representative Image and Descriptive Caption:

Enlarge
Interpolation from a coronal slice of a DTI using the nonlinear averaging. Original data is on the left; the right image is created by up-sampling the image by two.