2011 Summer Project Week Breakout Session EMRegistration

Summer Project Week Breakout Session: Registration for EM Segmenter

Wednesday, June 22, 2011, 3-4pm, Star room.

Synopsis:

The EM segmenter includes as a vital step the co-registration of a multiple subject atlas to obtain spatial priors for small region detection. The success of these priors depends heavily on the quality of the registration obtained. Because the registration includes a large-DOF nonrigid inter-subject registration, benchmarks for a good solution are largely absent. We seek an implementation of a registration using Slicer registration tools that will provide best possible robustness and if possible an estimate of reliability. Because this registration will be integrated into a slicer module, tools with a BSD license are strongly preferred.

Attendees (tentative):

• Kilian Pohl
• Dominik Meier
• Dominique Belhachemi
• Stephen Aylward
• Hans Johnson
• Bill Lorensen
• Jim Miller
• Allen Tannenbaum
• Daniel Haehn

Reference Material:

• Example case of 2 brains to register (.zip file, 16MB)

Preliminary Agenda:

• Description of the registration task for the EM segmenter
• Review of example case
• Comparison of BRAINSfit and CMTK strategies
• Discussion of design/implementation options/strategies

Meeting Notes:

• Hans pointed out that an upcoming fix, soon to be in ITK4, will incorporate an improved placement of control points, which reduces the need for masking
• CMTK takes ~1hr and is not a BSD license
• skull stripped input is not necessarily avail. for all input
• concatenation of multiple nonrigid transforms is also forthcoming in ITK4
• Plastimatch was not designed for brain MRI, but it does have multiresolution
• 2 track approach, using multiple versions that use different registration methods
• NA-MIC sandbox options: Andryi
• bootstrapping of transforms for saving time