Difference between revisions of "PA/A Tool"

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<h3>Objective</h3>
 
<h3>Objective</h3>
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*Calculate the ratio between the diameters of aorta and pulmonary artery, as a biomarker of acute exacerbations of COPD.
 
*Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification.
 
*Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification.
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For more information about the medical need:  
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For more information about the medical need: [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690810/?tool=pmcentrez Pulmonary Arterial Enlargement and Acute Exacerbations of COPD]
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*J. M. Wells, G. R. Washko, M. K. Han, N. Abbas, H. Nath, A. J. Mamary, E. Regan, W. C. Bailey, F. J. Martinez, E. Westfall, T. H. Beaty, D. Curran-Everett, J. L. Curtis, J. E. Hokanson, D. A. Lynch, B. J. Make, J. D. Crapo, E. K. Silverman, R. P. Bowler, M. T. Dransfield, the COPDGene and ECLIPSE Study Investigators, “Pulmonary Arterial Enlargement and Acute Exacerbations of COPD.,” N. Engl. J. Med., vol. 367, no. 10, pp. 913–921, Sep. 2012.
 
 
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Revision as of 19:39, 1 January 2015

Home < PA < A Tool

Key Investigators

Jorge Onieva, Rola Harmouche, German Gonzalez

Project Description

Objective

  • Calculate the ratio between the diameters of aorta and pulmonary artery, as a biomarker of acute exacerbations of COPD.
  • Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification.

For more information about the medical need: Pulmonary Arterial Enlargement and Acute Exacerbations of COPD

Approach, Plan

  • Phase 1:
    • Give the expert a simple mecanism to measure the aorta's major and minor axis in the best slide possible to detect calcification (this could include an automatic tool to detect which is the best slide)
    • Once the user has measured manually the two axis, calculate the ratio automatically.
  • Phase 2:
    • Completely automatic segmentation of the best slide and the two aorta axis for an expert validation.

Progress

  • First steps in aorta/pulmonary artery segmentation
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