Projects/Diffusion/2007 Project Week DTI Registration

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Key Investigators

• Utah: Ran Tao, Tom Fletcher, Ross Whitaker

Objective

We want to implement the Mutual Information metric using partial voluming for the registration of multi-modal images. The aim is to correct EPI distortions in diffusion-weighted images (DWIs).

Approach, Plan

Our approach is to register the DWIs to the baseline (B0) image using affine transformations and mutual information. We are implementing a version of MI that interpolates both joint histogram and partial voluming. This is smoother than the Mattes MI currently in ITK.

Progress

We have implemented PTV MI with 3D translation and 2D affine transformations.

Additional Information

Plot of MI versus xyz translation using PTV (T1 and T2 images)

Same plot using Mattes

Reference

• Wei.M, Liu.Jundong and Liu.Junhong Artifact reduction in mutual-information-based CT-MR image registration in Medical Imaging 2004: Image Processing
• Liu.J Artifacts reduction in mutual information-based image registration using prior information in Image Processing, 2003. ICIP 2003. Proceedings. 2003 International Conference