2007 APR NIH Questions and Answers

In a letter from Grace Peng, dated July 31 2007 the center team asks the following questions:

1. The weakest and probably most difficult parts of the NA-MIC effort are validation and comparison across algorithms. The validation that is being performed needs to be more systematic and coordinated like the tractography validation effort. Perhaps methods that engage the user community could be tried.
2. To what problems is DTI best applicable? Is it applicable across age ranges?
3. Although the NA-MIC Wiki contains information on who is using the NA-MIC kit and what are they using it for, the next annual report should either summarize this information or provide a link to the information. The next annual report should include a link and reference to the User Manual for the NA-MIC Kit.
4. What is the rational for choosing a particular method (tool) for solving a particular problem (DBP)? Why was a particular method (tool) chosen for development? Is there a listing of which tool might be helpful for which family of problems? Please provide more specific details to these questions as they have been asked previously by the Center Team.
5. A clinical project between Toronto and BWH still is recruitment phase in planning a DTI and genetic study of psychosis. What would be the genetic component?
6. The visualization tool allows the overlay of spherical, vector and ellipsoid data onto surfaces via versatile color maps. Is this extensible to other data, such a genetic or molecular data?
7. The achievements listed under Outreach and Technology Transfer are important in terms of linking to the engineering community and in terms of dissemination.