Events:Computational Methods for Radiation Oncology

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Date and Location

Date: Thursday, May 5, 2011

Location: Shapiro Boardroom, 70 Francis Street, Boston

Agenda

To brainstorm radonc computational methods between UNC, NA-MIC, BWH.

• 8:30-10am: UNC Presentations about current projects, short term and longer term plans
• 10am: Break
• 10:30-12pm: NA-MIC Presentations about current projects, term and longer term plans
• 12pm: Lunch
• 1-2:30pm: Identify Synergy areas
• 2:30-3pm: Break
• 3-4:30pm: Sketch out Mechanics for Collaboration

Agenda items from UNC

1. PLUNC: An open source complete radiation treatment planning system
   1. State of the art, GPU-based dose calculation
   2. Fast IMRT engine
   3. Image registration of unlimited number of images
   4. Manual segmentations in axial, coronal, and sagittal slices
   5. User interface via dials and other continuous controls
   6. Available on many operating systems and computers
   7. Used by ~100 institutions for research
   8. iHERO-compatible
   9. 3D visualization (see item 2)
2. 3D visualization in radiation treatment planning
   1. Integrated within PLUNC
   2. User interface: fully interactive pose and slice control, display entity control
      1. Single-GPU-based
   3. Methods:
   4. MGRview:
      1. Combinations of volume rendering, surface rendering, dose painting, beam outlines and views, …
      2. Object-coordinate based visualization operations for 3D visualization of multiple entities (objects, beams, dose, etc.) supported by texturing (2D and 3D)
      3. Illustration of object shape and position variations across days
3. Image analysis
   1. Skeletal model fitting to anatomic objects
   2. Skeletal model analysis into eigenmodes of variation and principal variances
   3. Segmentation via skeletal models and statistical models of image appearance (Pablo)
   4. Atlas to patient diffeomorphism calculation from corresponding reference object boundary points with correspondence maintenance
   5. Fluid-flow and control-theoretic greyscale diffeomorphism calculation
   6. IGRT from 2D projections to 3D CTs
      1. Registration
      2. CT reconstructions at treatment time therefrom
4. Utilities: Anti-aliased manual segmentations
5. Applications: Endoscopy/CT fusion in head and neck: registration and visualization (early stages)

Agenda items from NA-MIC

1. Works in Progress on RT
   1. DICOM RT Support Roadmap and Head and Neck Cancer Application Summary(Greg Sharp)
   2. Pelvic Applications Summary (Tina)
2. Slicer Roadmap and its relevance to RT

Agenda items from Harvard, MGH

• Shadie, shading language for volume visualization(Hanspeter Pfister, Milos Hasan, George Chen, John Wolfgang)

Participants

Confirmed Attendees:

1. Derek Merck
2. Hina Shah
3. Stephen Pizer
4. Brandon Frederick
5. Ilknur Kabul
6. Gregg Tracton
7. Sandy Wells
8. James Balter
9. Hanspeter Pfister
10. Ron Kikinis
11. John Wolfgang
12. Steve Pieper
13. Andrey Fedorov
14. George Chen
15. Tina Kapur

This is a tentative list of participants. No one has been contacted yet.

1. Julian Rosenman, UNC
2. Steve Pizer, UNC
3. Sha Chang, UNC
4. Dave Lalush, UNC
5. Ron Alterovitz, UNC
6. Derek Merck, UNC
7. Ilknur Kaynar-Kabul, UNC
8. Hina Shah, UNC
9. Chen-Rui Chou, UNC
10. Lei Pan, UNC
11. Brandon Frederick, UNC
12. Clare Tempany, BWH
13. Robert Cormack, BWH
14. Greg Sharp, MGH
15. Andrey Federov, BWH
16. Ron Kikinis, BWH
17. Hans Peter Pfister, Harvard
18. George Chen, MGH
19. John Wolfgang MGH
20. Milos Hasan MGH alum/Berkeley
21. Tina Kapur, BWH
22. James Balter, Michigan
23. Gabor Fichtinger, Queens
24. Terry Yoo, NLM
25. Dave Chen, NLM
26. James Deye, NCI
27. Stephen Aylward, Kitware
28. Steve Pieper, Isomics