Events:Computational Methods for Radiation Oncology

 Back to Events

Date and Location

Date: Thursday, May 5, 2011

Location: Surgery Education Office, Room CA-034, Carrie Hall, 15 Francis Street. (Directions)

In addition, the following information is useful for first time visitors to the hospital:

• http://www.brighamandwomens.org/about_bwh/locations/directions/default.aspx
• On the "Pike map" PDF link (bottom of page), the Carrie Hall building is closest to the 15 Francis St entrance -- enter through the columns.
• On Google Street View/Map, the Carrie Hall building is near the label "Howard Hughes Medical Institute".

Agenda

To brainstorm computational methods for radiation oncology between UNC, NA-MIC, BWH.

• 8am: Breakfast
• 8:30-10:30am: UNC -presentations about capabilities of current projects, short term and longer term plans
  • Julian Rosenman PLUNC 18 minutes
  • Gregg Tracton Software for PLUNC, segmentation, registration 10 minutes
  • Stephen Pizer Registration by regression (2 methods), Segmentation via posterior optimization, training probability distributions on s reps and quantile functions, segmentation via correspondence-preserving warps, ant aliasing 23 minutes
  • Sha Chang Nanotube imaging, incl. for IGRT 10 minutes
  • Brandon Frederick Iterative tomographic reconstruction, CTs at treatment time, gpu’s 15 minutes
  • Derek Merck 3D visualization via model-guided rendering, 3D visualization in PLUNC for RTP 15 minutes
  • Ilknur Kabul Texturing of surfaces, onion skins, and cut planes; interpolation of textures 10 minutes
  • Hina Shah Registration of endoscopic cine and CT of throat,fused displays of these two registered sources 8 minutes
  • Ron Alterovitz Planning for brachytherapy with curved needles, FEM software 12 minutes
• 10:30 am: Break
• 11:50am-2:30pm NA-MIC/Harvard presentations about capabilities of current projects, short term and longer term plans
  • AMIGO (Tina Kapur) (5 minutes)
  • Slicer3 to Slicer 4, Radiation Therapy support today, and plans for the next year (slides) (Steve Pieper) (30 minutes)
  • SPARKit, Canadian grant for providing open source software platform for radiotherapy, potentially based on NA-MIC Kit (slides) (Andras Lasso) (10minutes)
  • Head and Neck Cancer NA-MIC DBP (slides) (Greg Sharp) (15 minutes)
  • Gynecologic Cancer Brachytherapy Plans (Tina Kapur) (10 minutes)
  • Shadie, shading language for volume visualization (Hanspeter Pfister, Milos Hasan, George Chen, John Wolfgang) (20 minutes)
• Continue presentations...
• 2:30pm: Intro of afternoon objectives (Julian Rosenman)
• 2:45pm: What UNC/Boston system combinations ought to be developed -- the Boston perspective (Tina Kapur)
• 3pm: What Boston/UNC system combinations ought to be developed -- the UNC perspective (Steve Pizer)
• 3:30pm: Comments from Kitware about their capabilities relevant to proposed combinations (Brad Davis)
• 4-5pm
  • Break and subgroup formation (e.g., merging surgical and radiation treatment planning system; 3D visualization software for treatment planning; image analysis software for treatment planning)
  • Subgroups sketch out mechanics for collaborations (http://grants.nih.gov/grants/guide/pa-files/PAR-11-028.html?)
  • Summary: what we do next?

Confirmed Participants

1. Julian Rosenman
2. Gregg Tracton
3. Stephen Pizer
4. Sha Chang
5. Brandon Frederick
6. Derek Merck
7. Ilknur Kabul
8. Hina Shah
9. Ron Alterovitz
10. Ron Kikinis
11. Sandy Wells
12. Steve Pieper
13. Andras Lasso
14. Greg Sharp
15. Tina Kapur
16. Hanspeter Pfister
17. Milos Hasan
18. George Chen
19. John Wolfgang
20. Petter Risholm
21. Andrey Fedorov
22. James Balter
23. Brad Davis
24. Andinet Enquobahrie
25. Firdaus Janoos

Potential Areas of Collaboration

Slicer/NA-MIC has • Multimodal registration algorithms • How to put UNC code into the open source world (from BWH experience – third party? Assembla? Check with Queens/Andras) •

PLUNC has • Tolerance and other surface color washes on textured objects • Endoscopy and 3D MR segmentation: cervix •

Both want

• Hanging Protocol from Radiology – take bookmarks/scene views from one patient and apply to another • Shadie/MGRView integration • AMIGO w/ endoscopy • AMIGO w/ curved needles • Meet IHERO standards for communication with Pinnacle/Eclipse

Additional

• ITK needs GPU support •

Optical CT inclusion

FEM modeling sharings between BWH and UNC

Robotics and device tracking sharing: BWH has device tracking expertise (openIGTLink)

Shadie/MGRView integration

Adding cmake to PLUNC

Problem: how to integrate object-based coordinate systems into object models and integrate UI controls within those coordinate systems?

MGRView w/ ray-cast volume rendering a la volview/vtk

Inclusion of Ontario ARKit/SparKir? (adaptive RT)

What can be taken from PLUNC into Slicer right away?

There needs to be a remodeling of PLUNC licensing to meet the Slicer sharing philosophy

US MR or CT registration brought to RT (Balter putting in a grant on this)

Visualize uncertainty by painting over texture (Pfister/UNC)

Combine Shadie language with MGRView/PLUNC 3Dview capabilities

Image anal and visualization via Slicer (selected modules in use) into PLUNC into MOSAIQ, etc.

•PLUNC Need: Flexibility/refactor? • Multimodal registration.

•Is there a role for python, numpy?

•Note: WashU CERR has a simple dose engine.

•2d-3d Registration for IGRT using Nanotube Statitionary STomosynthesis from Siemens, Xinray

•Head and Neck Segmentation by registration and refinement

•Antialiasing algorithm

•How will antialiasing impact DVHs? What is the drift in the dose distribution

•Morphomics Segmentation software for Prostate and Cervix maybe

•James balter collaboration LA problem

•ITK should have GPU support

•Potential tools from UNC: –Iterative reconstruction software is shareable

–General GPU tools

•Manual Editing of alignment

•Dose accumulation calculation

•Mechanisms –Software maintenance R01

–BRP collaborative grant

•Registration of endoscopic images with CT for IGRT: Gyn colposcopy

•Steerable needle planning for gyne brachytherapy

•How to close the loop with feedback for needle insertion and steering for prostate brachy?

Open FEM standard for RT (Balter): How to tie FEMs for creating shape descriptors.