Difference between revisions of "2011 Summer Project Week Shape Analysis UNC"

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<h3>Approach, Plan</h3>
 
<h3>Approach, Plan</h3>
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The developed shapeAnalysisMANCOVA is a C++ program that can be run both with shapeAnalysisMANCOVA_Wizard as well as a command line tool. In order to compile shapeAnalysisMANCOVA, ITK, VTK, GenerateCLP and Boost Libraries for C (v 0.39.1) must already be installed.
 
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The point-based models will be analyzed with methods using multivariate analysis of covariance (MANCOVA).
 
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The steps performed in order to obtain the statistical analysis are the following, for each iteration:
 
  
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computing a General Linear Model (GLM) to test group differences at every surface location,
 
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doing the Metric computation thanks to the Multivariate analysis of covariance (MANCOVA),
 
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computing the P-values and controlling for the mutliple testing problem,
 
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doing the permutations tests (considering the linear varibles).
 
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The data scenes (MRML scene) are created and can be displayed within 3D Slicer.
 
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Our plan for the project week is to:
 
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* try to get rid of boost library - find similar method in Slicer libraries if possible
 
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* use GenerateCLP to integrate shapeAnalysisMANCOVA_Wizard directly within Slicer3
 
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* Load MRML scenes created for quality control directly within Slicer
 
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* improve the shapeAnalysisMANCOVA_Wizard
 
  
 
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Revision as of 15:41, 25 May 2011

Home < 2011 Summer Project Week Shape Analysis UNC

  • Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.

  • Regression of FA data; solid line represents the mean and dotted lines the standard deviation.

Key Investigators

  • UNC: Lucile Bompard, Clement Vachet,Beatriz Paniagua,Martin Styner
  • ......

Objective

The UNC shape analysis framework is an automatic approach employing sampled spherical harmonics (SPHARM-PDM). ShapeAnalysisModule computes point-based models using a parametric boundary description. The goal is to be able to use the point-based models computed with this tool to perform statistical studies (within shapeAnalysisMANCOVA) or to get correspondence point Models(within ParticleModule).


Approach, Plan


Progress

shapeAnalysisMANCOVA_Wizard can be use either though command line or within Slicer and whatever the choise, the mrml scene will be displayed in Slicer3 at the end. The shapeAnalysisMANCOVA_Wizard's window is now resizable.


Delivery Mechanism

This work will be delivered to the NA-MIC Kit as a

  1. ITK Module
  2. Slicer Module
    1. Built-in
    2. Extension -- commandline YES
    3. Extension -- loadable YES
  3. Other shapeAnalysisMANCOVA_Wizard
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