2012 Winter Project Week:GBMseg

Key Investigators

• WUSM: Dan Marcus, Misha Milchenko
• Brigham and Women's: Andrey Fedorov, Jan Egger

Objective

We are looking to segment and visualize GBM's from various MR sequences in Slicer, and create an integrated display for clinician review, both radiologist and non-radiologist.

Approach, Plan

The approach is to obtain accurate registration of a number of MR sequences of each tumor case, and analyze correlation with pathology data.

Progress

Delivery Mechanism

GBM MR preprocessing pipeline

References

GrowCut segmentation Slicer documentation: http://wiki.slicer.org/slicerWiki/index.php/Modules:GrowCutSegmentation-Documentation-3.6

V. Vezhnevets and V. Konouchine, "GrowCut - Interactive multi-label N-D image segmentation," in Proc. Graphicon, 2005. pp. 150--156.

Mark Jenkinson, Stephen Smith. "Optimisation in Robust Linear Registration of Brain Images." FMRIB Technical Report TR00MJ2, http://www.fmrib.ox.ac.uk/analysis/techrep/tr00mj2/tr00mj2/