Difference between revisions of "2013 Summer Project Week:Epilepsy Surgery"

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(Created page with '__NOTOC__ <gallery> Image:PW-MIT2013.png|Projects List Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus…')
 
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<gallery>
 
Image:PW-MIT2013.png|[[2013_Summer_Project_Week#Projects|Projects List]]
 
Image:genuFAp.jpg|Scatter plot of the original FA data through the genu of the corpus callosum of a normal brain.
 
Image:genuFA.jpg|Regression of FA data; solid line represents the mean and dotted lines the standard deviation.
 
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==Instructions for Use of this Template==
 
#Please create a new wiki page with an appropriate title for your project using the convention 2013_Winter_Project_Week:<Project Name>
 
#Copy the entire text of this page into the page created above
 
#Link the created page into the list of projects for the project event
 
#Delete this section from the created page
 
#Send an email to tkapur at bwh.harvard.edu if you are stuck
 
  
 
==Key Investigators==
 
==Key Investigators==
* UNC: Isabelle Corouge, Casey Goodlett, Guido Gerig
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* USP - Luiz Murta
* Utah: Tom Fletcher, Ross Whitaker
 
  
 
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<h3>Objective</h3>
 
<h3>Objective</h3>
We are developing methods for analyzing diffusion tensor data along fiber tracts. The goal is to be able to make statistical group comparisons with fiber tracts as a common reference frame for comparison.
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This project will investigate the presence and location of the epileptogenic focus by analyzing patterns of texture in magnetic resonance imaging (MRI) after segmentation using anisotropic diffusion filters anomalous and geodesic active contour.
  
  
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<h3>Progress</h3>
 
<h3>Progress</h3>
Software for the fiber tracking and statistical analysis along the tracts has been implemented. The statistical methods for diffusion tensors are implemented as ITK code as part of the [[NA-MIC/Projects/Diffusion_Image_Analysis/DTI_Software_and_Algorithm_Infrastructure|DTI Software Infrastructure]] project. The methods have been validated on a repeated scan of a healthy individual. This work has been published as a conference paper (MICCAI 2005) and a journal version (MEDIA 2006). Our recent IPMI 2007 paper includes a nonparametric regression method for analyzing data along a fiber tract.
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Methods for segmentation and texture features extraction are written into ITK
  
  
 
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==Delivery Mechanism==
 
 
This work will be delivered to the NA-MIC Kit as a (please select the appropriate options by noting YES against them below)
 
 
#ITK Module
 
#Slicer Module
 
##Built-in
 
##Extension -- commandline
 
##Extension -- loadable
 
#Other (Please specify)
 
  
 
==References==
 
==References==
*Fletcher P, Tao R, Jeong W, Whitaker R. [http://www.na-mic.org/publications/item/view/634 A volumetric approach to quantifying region-to-region white matter connectivity in diffusion tensor MRI.] Inf Process Med Imaging. 2007;20:346-358. PMID: 17633712.
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*Shaker, M. & Soltanian-Zadeh, H., 2008. Voxel-Based Morphometric Study of Brain Regions from Magnetic Resonance Images in Temporal Lobe Epilepsy. Image Analysis and Interpretation, 2008. SSIAI 2008. IEEE Southwest Symposium on, 209-212.
* Corouge I, Fletcher P, Joshi S, Gouttard S, Gerig G. [http://www.na-mic.org/publications/item/view/292 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Med Image Anal. 2006 Oct;10(5):786-98. PMID: 16926104.
 
* Corouge I, Fletcher P, Joshi S, Gilmore J, Gerig G. [http://www.na-mic.org/publications/item/view/1122 Fiber tract-oriented statistics for quantitative diffusion tensor MRI analysis.] Int Conf Med Image Comput Comput Assist Interv. 2005;8(Pt 1):131-9. PMID: 16685838.
 
* Goodlett C, Corouge I, Jomier M, Gerig G, A Quantitative DTI Fiber Tract Analysis Suite, The Insight Journal, vol. ISC/NAMIC/ MICCAI Workshop on Open-Source Software, 2005, Online publication: http://hdl.handle.net/1926/39 .
 

Revision as of 20:29, 23 May 2013

Home < 2013 Summer Project Week:Epilepsy Surgery


Key Investigators

  • USP - Luiz Murta

Objective

This project will investigate the presence and location of the epileptogenic focus by analyzing patterns of texture in magnetic resonance imaging (MRI) after segmentation using anisotropic diffusion filters anomalous and geodesic active contour.




Approach, Plan

Our approach for analyzing diffusion tensors is summarized in the IPMI 2007 reference below. The main challenge to this approach is <foo>.

Our plan for the project week is to first try out <bar>,...

Progress

Methods for segmentation and texture features extraction are written into ITK


References

  • Shaker, M. & Soltanian-Zadeh, H., 2008. Voxel-Based Morphometric Study of Brain Regions from Magnetic Resonance Images in Temporal Lobe Epilepsy. Image Analysis and Interpretation, 2008. SSIAI 2008. IEEE Southwest Symposium on, 209-212.