Difference between revisions of "2014 Project Week:CardiacCongenitalSegmentation"
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* Also tried affine registrations across my 5 subjects, using BRAINSFIT | * Also tried affine registrations across my 5 subjects, using BRAINSFIT | ||
** Works very roughly, as expected | ** Works very roughly, as expected | ||
+ | * Next steps: | ||
+ | ** Try Carrera on additional datasets for blood pool segmentation | ||
+ | ** Myocardium segmentation is still a challenge | ||
* Thanks to: Josh Cates, Salma Bengali, Yi Gao, Ivan Kolesov for your help and suggestions! | * Thanks to: Josh Cates, Salma Bengali, Yi Gao, Ivan Kolesov for your help and suggestions! | ||
</div> | </div> | ||
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Latest revision as of 15:15, 10 January 2014
Home < 2014 Project Week:CardiacCongenitalSegmentationKey Investigators
Danielle Pace, MIT
Polina Golland, MIT
Project Description
Objective
- Develop a semi-automatic segmentation algorithm for cardiac MR images of patients with congenital heart defects.
- Goal is to build a surface model showing the endocardial and epicardial boundaries, for surgical planning.
- Challenges:
- Very large inter-subject variability due to heart defects
- Intensity inhomogeneities within myocardium and blood pool
- Similar intensity distributions within adjacent tissues (e.g. liver, chest muscle)
Approach, Plan
- Try existing open-source tools for segmentation and registration on the five datasets that we have so far.
- See where these methods fail, to focus our efforts for developing algorithms for segmenting hearts with congenital defects.
Progress
- Focused on blood pool segmentation in one test case. Tried:
- CARMA tools: isolated connected / connected threshold operators
- Editor level tracing effect
- Editor Fast Marching effect
- Editor Grow Cuts effect
- Carrera interactive segmentation
- Robust statistic active contour segmentation
- Best tool = Carrera interactive segmentation
- Main difficulty = small chamber/vessel walls assigned as blood pool, but these can be fixed within Carrera somewhat easily
- Also tried affine registrations across my 5 subjects, using BRAINSFIT
- Works very roughly, as expected
- Next steps:
- Try Carrera on additional datasets for blood pool segmentation
- Myocardium segmentation is still a challenge
- Thanks to: Josh Cates, Salma Bengali, Yi Gao, Ivan Kolesov for your help and suggestions!