Difference between revisions of "2014 Summer Project Week:Stroke-ImagingGenetics"
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Image:PW-MIT2014.png|[[2014_Summer_Project_Week#Projects|Projects List]] | Image:PW-MIT2014.png|[[2014_Summer_Project_Week#Projects|Projects List]] | ||
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Image:Leuk_model.png|Leukoaraiosis Model | Image:Leuk_model.png|Leukoaraiosis Model | ||
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==Key Investigators== | ==Key Investigators== |
Revision as of 14:30, 23 June 2014
Home < 2014 Summer Project Week:Stroke-ImagingGenetics
Key Investigators
- Adrian Dalca, Ramesh Sridharan, Polina Golland, MIT
- Natalia Rost, Jonathan Rosand, MGH
Project Description
This is one of a series of projects on a large clinical dataset of stroke patients, including T2-FLAIR and DWI imaging. We recently (MICCAI 2014) developed a leukoaraiosis (small vessel disease) probabilistic co-variation model, which we use to differentiate between small vessel disease and acute or chronic stroke on T2-FLAIR.
Average Leukoaraiosis projection
Explore the first component of the model
Objective
- Here, we wish to investigate the parameters of the model as potential phenotypes against for clinical and genetic analyses.
Approach, Plan
- We will create the phenotype projections for ~80 stroke patients and experiment with correlating the genetic and clinical factors.