Difference between revisions of "PA/A Tool"
From NAMIC Wiki
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<h3>Objective</h3> | <h3>Objective</h3> | ||
*Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification. | *Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification. | ||
| + | For more information about the medical need: | ||
| + | *J. M. Wells, G. R. Washko, M. K. Han, N. Abbas, H. Nath, A. J. Mamary, E. Regan, W. C. Bailey, F. J. Martinez, E. Westfall, T. H. Beaty, D. Curran-Everett, J. L. Curtis, J. E. Hokanson, D. A. Lynch, B. J. Make, J. D. Crapo, E. K. Silverman, R. P. Bowler, M. T. Dransfield, the COPDGene and ECLIPSE Study Investigators, “Pulmonary Arterial Enlargement and Acute Exacerbations of COPD.,” N. Engl. J. Med., vol. 367, no. 10, pp. 913–921, Sep. 2012. | ||
</div> | </div> | ||
<div style="width: 27%; float: left; padding-right: 3%;"> | <div style="width: 27%; float: left; padding-right: 3%;"> | ||
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* Phase 2: | * Phase 2: | ||
** Completely automatic segmentation of the best slide and the two aorta axis for an expert validation. | ** Completely automatic segmentation of the best slide and the two aorta axis for an expert validation. | ||
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</div> | </div> | ||
<div style="width: 27%; float: left; padding-right: 3%;"> | <div style="width: 27%; float: left; padding-right: 3%;"> | ||
Revision as of 13:39, 31 December 2014
Home < PA < A Tool
Key Investigators
Jorge Onieva, Rola Harmouche, German Gonzalez
Project Description
Objective
- Calculate in a fast way the ratio of the major and minor axis of the aorta in a chest CT slice where the pulmonary artery is clearly visible. This ratio is a biomarker used to detect aorta calcification.
For more information about the medical need:
- J. M. Wells, G. R. Washko, M. K. Han, N. Abbas, H. Nath, A. J. Mamary, E. Regan, W. C. Bailey, F. J. Martinez, E. Westfall, T. H. Beaty, D. Curran-Everett, J. L. Curtis, J. E. Hokanson, D. A. Lynch, B. J. Make, J. D. Crapo, E. K. Silverman, R. P. Bowler, M. T. Dransfield, the COPDGene and ECLIPSE Study Investigators, “Pulmonary Arterial Enlargement and Acute Exacerbations of COPD.,” N. Engl. J. Med., vol. 367, no. 10, pp. 913–921, Sep. 2012.
Approach, Plan
- Phase 1:
- Give the expert a simple mecanism to measure the aorta's major and minor axis in the best slide possible to detect calcification (this could include an automatic tool to detect which is the best slide)
- Once the user has measured manually the two axis, calculate the ratio automatically.
- Phase 2:
- Completely automatic segmentation of the best slide and the two aorta axis for an expert validation.
Progress
- First steps in aorta/pulmonary artery segmentation
