Difference between revisions of "2015 Summer Project Week:T1 mapping"

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==Project Description==
 
==Project Description==
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T1 mapping estimates effective tissue parameter maps (T1) from multi-spectral FLASH MRI scans with different flip angles. T1 mapping can be used to optimize parameters for a sequence, monitor diseased tissue, measure Ktrans in DCE-MRI and etc.
 
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* Start with prostate diffusion module
 
* Start with prostate diffusion module
 
* Update equations for T1 mapping
 
* Update equations for T1 mapping
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* Compare the results using C++, [http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/T1_Mapping Python], [https://surfer.nmr.mgh.harvard.edu/fswiki/mri_ms_fitparms  Freesurfer ] with ground truth of T1 for [https://dblab.duhs.duke.edu/modules/QIBAcontent/index.php?id=1  QIBA phantom]
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* Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles
  
 
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<h3>Progress</h3>
 
<h3>Progress</h3>
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* Equations have already been updated
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* Working on the GUI
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* Working on the comparison
 
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==References==
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* [https://dblab.duhs.duke.edu/modules/QIBAcontent/index.php?id=1  QIBA T1 phantom]
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* [http://europepmc.org/articles/pmc3620726 Basic equation for T1]

Revision as of 21:00, 20 June 2015

Home < 2015 Summer Project Week:T1 mapping

Key Investigators

  • Xiao Da (MGH), Yangming Ou (MGH), Andriy Fedorov (BWH), Jayashree Kalpathy-Cramer (MGH)

Project Description

T1 mapping estimates effective tissue parameter maps (T1) from multi-spectral FLASH MRI scans with different flip angles. T1 mapping can be used to optimize parameters for a sequence, monitor diseased tissue, measure Ktrans in DCE-MRI and etc.

Objective

  • Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles
  • Implement T1 mapping algorithm as a Slicer extension using C++

Approach, Plan

  • Start with prostate diffusion module
  • Update equations for T1 mapping
  • Compare the results using C++, Python, Freesurfer with ground truth of T1 for QIBA phantom
  • Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles

Progress

  • Equations have already been updated
  • Working on the GUI
  • Working on the comparison

References