Difference between revisions of "2015 Summer Project Week:T1 mapping"
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<h3>Objective</h3> | <h3>Objective</h3> | ||
* Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles | * Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles | ||
− | * Implement T1 mapping algorithm as a Slicer | + | * Implement T1 mapping algorithm as a Slicer module using C++ |
</div> | </div> | ||
<div style="width: 27%; float: left; padding-right: 3%;"> | <div style="width: 27%; float: left; padding-right: 3%;"> | ||
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* Start with [http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/DWModeling prostate diffusion module] | * Start with [http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/DWModeling prostate diffusion module] | ||
* Update equations for T1 mapping | * Update equations for T1 mapping | ||
− | * Compare the results using C++, [http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/T1_Mapping Python], [https://surfer.nmr.mgh.harvard.edu/fswiki/mri_ms_fitparms Freesurfer ] with ground truth of T1 for [https://dblab.duhs.duke.edu/modules/QIBAcontent/index.php?id=1 QIBA phantom] | + | * Compare the results using C++, [http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/T1_Mapping Python], [https://surfer.nmr.mgh.harvard.edu/fswiki/mri_ms_fitparms Freesurfer ] with the ground truth of T1 for [https://dblab.duhs.duke.edu/modules/QIBAcontent/index.php?id=1 QIBA phantom] |
* Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles | * Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles | ||
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<div style="width: 27%; float: left; padding-right: 3%;"> | <div style="width: 27%; float: left; padding-right: 3%;"> | ||
<h3>Progress</h3> | <h3>Progress</h3> | ||
− | * | + | * Updated the equation for variable flip angle (VFA) T1 mapping |
− | * | + | * Compared the results using C++ with Python, Freesurfer and the ground truth of T1 for QIBA phantom data |
− | * | + | * T1 mapping results on QIBA phantom data using C++ are comparable with the ground truth and the results using Freesurfer and Python |
+ | * Did some tests on MGH Brain Tumor MR Data with multiple flip angles | ||
+ | * Created a module for T1 mapping using C++ | ||
+ | ** Take multi-spectral FLASH images with an arbitrary number of flip angles as input, and estimate the T1 values of the data for each voxel | ||
+ | ** Read repetition time(TR), echo time(TE) and flip angles from the Dicom header automatically | ||
+ | ** Allow user to choose which flip angles will be included or excluded for the fitting process | ||
+ | ** Output the fitting volume and quality of fitting image as well | ||
+ | * Uploaded the source code on Github | ||
</div> | </div> | ||
</div> | </div> |
Revision as of 09:59, 24 June 2015
Home < 2015 Summer Project Week:T1 mappingKey Investigators
- Xiao Da (MGH), Yangming Ou (MGH), Andriy Fedorov (BWH), Jayashree Kalpathy-Cramer (MGH)
- Utsav Pardasani (Observing)
Project Description
T1 mapping estimates effective tissue parameter maps (T1) from multi-spectral FLASH MRI scans with different flip angles. T1 mapping can be used to optimize parameters for a sequence, monitor diseased tissue, measure Ktrans in DCE-MRI and etc.
Objective
- Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles
- Implement T1 mapping algorithm as a Slicer module using C++
Approach, Plan
- Start with prostate diffusion module
- Update equations for T1 mapping
- Compare the results using C++, Python, Freesurfer with the ground truth of T1 for QIBA phantom
- Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles
Progress
- Updated the equation for variable flip angle (VFA) T1 mapping
- Compared the results using C++ with Python, Freesurfer and the ground truth of T1 for QIBA phantom data
- T1 mapping results on QIBA phantom data using C++ are comparable with the ground truth and the results using Freesurfer and Python
- Did some tests on MGH Brain Tumor MR Data with multiple flip angles
- Created a module for T1 mapping using C++
- Take multi-spectral FLASH images with an arbitrary number of flip angles as input, and estimate the T1 values of the data for each voxel
- Read repetition time(TR), echo time(TE) and flip angles from the Dicom header automatically
- Allow user to choose which flip angles will be included or excluded for the fitting process
- Output the fitting volume and quality of fitting image as well
- Uploaded the source code on Github