Projects/Diffusion/2007 Project Week DTI Registration

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Key Investigators

• Utah: Ran Tao, Tom Fletcher, Ross Whitaker

Objective

We want to implement the Mutual Information metric using partial voluming for the registration of multi-modal images. The aim is to correct EPI distortions in diffusion-weighted images (DWIs).

Approach, Plan

Our approach is to register the DWIs to the baseline (B0) image using affine transformations and mutual information. We are implementing a version of MI that interpolates both joint histogram and partial voluming. This is smoother than the Mattes MI currently in ITK.

Progress

• 3D mutual information metric has been implemented
• Register T2 diffusion weighted image to its own baseline T2 image