Mbirn: Open Access Structural Imaging Series

• Short Description
  • The Open Access Structural Imaging Series (OASIS) is a series of structural MRI data sets that is being made publicly available for study and analysis. This initial data set consists of a cross-sectional collection of 400 subjects covering the adult life span. For each subject, 3 or 4 individual T1-weighted MRI scans obtained in single scan sessions are included. The subjects are all right-handed and approximately equally divided by gender. 100 of the included subjects over the age of 60 have been diagnosed with very mild to mild dementia of the Alzheimer's type (DAT). Additionally, a reliability data set of images obtained from 20 of the non-demented subjects on a subsequent visit are included. The data are amenable to a range of analytic approaches. Measures, including automated computations of whole brain volume and estimated total intracranial volume are presented as a demonstration of approaches that capture fundamental change in brain structure in healthy and diseased aging. A web-based application is available for visualizing, exploring, and downloading the data set.

• Status
  • The OASIS manuscript and web application are currently in preparation. The first set in the series will be presented as a poster at Society for Neuroscience in November 2005. OASIS data will be released under an unrestrictive open license.

• Keywords
  • MRI, open access, public access, Alzheimer's disease, aging

• Longer Overview

• User Manual

• Registration, download and installation information
  • Upon release, the data can be downloaded directly from BIRN or from http://www.oasis-brains.org

• References

• Technical Contact
  • Dan Marcus (dmarcus@wustl.edu)

• Acknowledgements

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