DBP3:Utah:RegSegPipeline

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The CARMA DBP: MRI-based study and treatment of atrial fibrillation

Pilot Studies on a Registration & Segmentation Pipeline & Workflow

• Overall processing steps are (order tentative)
  • coarse registration MRA>cMRI
  • ROI definition (manual box ROI or automated via atlas)
  • N4 bias field correction for the MRI (surface coils): requires definition of ROI, unlikely to be successful on entire image
  • refined registration intra subject MRA->cMRI
  • segmentation of LA from MRA -> inner wall
  • segmentation of LA wall
  • segmentation of enhancement within LA wall: intensity statistics
  • registration follow-up -> baseline

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  Example contrast MRI with thresholded MRA as color overlay

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  Example contrast MRI with thresholded MRA as color overlay and areas of enhancement marked