2012 Summer Project Week:DifficultRegistration

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Projects List

Registration Result Visualization

Slicer:BRAINS

NiftyReg

SIFT Landmark

Key Investigators

Erasmus Medical Center: Stefan Klein
University College London: Marc Modat
UNC: Aditya Gupta, Martin Styner
BWH: Matthew Toews, Petter Risholm, Dominik Meier, William Wells

Objective

To identify solutions to difficult image registration problems that challenge the limits of current technology. Aspects of difficulty will include:

inter-subject registration
truncation, missing tissue
unknown initialization
inter-species registration
articulated deformation

Approach, Plan

A set of difficult pair-wise registration problems will be considered. Participants will discuss workable solutions based on their expertise and background, and these solutions will be documented.
Registration cases can be found here.

CT: atlas and torso have flipped orientation: Correction Xforms here: Flip CT atlas&torso, zip file with 2 .tfm files

Progress

We held a general discussion of registration challenges in the community. Three registration approaches were evaluated on test data: (NiftyReg), (BrainsFit), (SIFT Landmarks).

Registration of difficult brain images is successful, body images remain challenging.
Masking of problematic image regions, e.g. pathology, is an important but time-consuming pre-processing task that could be further investigated or automated. For instance, interactive masking/segmentation of pathology, linking registration and masking.
Registration direction has an important impact, i.e. which images are designed as fixed or moving. Symmetric or bi-directional registration is helpful.

Delivery Mechanism

Attention Participants: Please log in and update/correct entries in the table below. For bonus points, please provide links or solutions to image registration problems on this page.

Participant	Affiliation	Context	Techniques	Solutions/Links
Steven Aylward	Kitware	CT, US, ressection, brain tumors, changing pathology, sliding organ	Sliding Geometry, Geometric Metamorphosis
Karl Diedrich	AZE	Rigid registration, abdomen	Multi-resolution registration
James Fishbaugh	SCI	Shape analysis and registration
Aditya Gupta	UNC	DTI, enlarged lateral ventricles
Stefan Klein	Erasmus Medical Center	General Registration
Ivan Kolesov	Georgia Tech	Articulated, point-based registration	Plastimatch, NiftyReg	Head Neck Results
Dominik Meier	BWH	General registration	Slicer: BRAINS	IntraOp: TBI: CT torso: FAILED
Marc Modat	UCL	neuro-deg. diseases, longitudinal	NiftiReg	Some test res
Albert Motillo	GE	Parsing CT, Detection
Simrin Nagpal	Queens University	CT/US registration
Samon Nuranian	UBC	US-guided intervension, spine
Andre Remi	UCLA	Longitudinal changes in TBI, tissue types
Peter Risholm	BWH	Brain, head and neck, radiation therapy	Probabilistic Uncertainty
Samira Sojoudi	UBC	Spine, CT/US registration
Matthew Toews	BWH	General registration	SIFT landmark correspondence	MR-brain: CT-torso:
Bo Wang	Utah	TBI image segmentation
Kevin Wang	Princess Margaret Hospital	Adaptive radiation therapy, longitudinal
William Wells	BWH	Interventional applications	Theory: Segmentation, Registration