2013 Winter Project Week:Hybrid registration

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Key Investigators

  • Nadya Shusharina, Greg Sharp, MGH
  • Steve Pieper, Isomics


We propose to augment B-spline deformable registration with landmark information. Matching of landmarks is performed by the optimization procedure applied to the cost function containing an intensity-based data term and two constraints, smoothing and an explicit landmark matching.

Objective

  • To develop the method to extend automatic algorithm of deformable image registration based on B-spline approximation
  • The method includes landmark matching in the form of explicit landmark constraint
  • The method is relevant for fast registrations that require matching of certain image features

Approach, Plan

  • To introduce CLI in Slicer 4 as a part of Plastimatch Registration module
  • Try the algorithm on various data sets

Progress

We extended Plastimatch B-spline deformable registration module with landmark matching functionality. We tested the new feature on synthetic image and obtained satisfactory results. We set future goal to work on interactive real-time landmark placing.

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