2015 Summer Project Week:T1 mapping

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Key Investigators

  • Xiao Da (MGH), Yangming Ou (MGH), Andriy Fedorov (BWH), Jayashree Kalpathy-Cramer (MGH)

Project Description

T1 mapping estimates effective tissue parameter maps (T1) from multi-spectral FLASH MRI scans with different flip angles. T1 mapping can be used to optimize parameters for a sequence, monitor diseased tissue, measure Ktrans in DCE-MRI and etc.

Objective

  • Estimate effective T1 from multi-spectral FLASH MRI scans with different flip angles
  • Implement T1 mapping algorithm as a Slicer extension using C++

Approach, Plan

  • Start with prostate diffusion module
  • Update equations for T1 mapping
  • Compare the results using C++, Python, Freesurfer with ground truth of T1 for QIBA phantom
  • Test the Slicer module on MGH Brain Tumor MR Data with multiple flip angles

Progress

  • Equations have already been updated
  • Working on the GUI
  • Working on the comparison

References

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