2009 Winter Project Week Tumor Microenvironment

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Key Investigators

• The Ohio State University: Shantanu Singh, Raghu Machiraju
• GE Global Research: Jens Rittscher
• BWH: Michael Halle, Steve Pieper, Wendy Plesniak

Objective

To implement a microscopy image analysis pipeline in Slicer3, specifically tailored for characterizing the tumor microenvironment as observed in the murine breast tumors.

Approach, Plan

Integrate existing segmentation, validation and labeling pipelines into the Slicer3 framework. Begin with level set methods of Mosaliganti et al. Then the tessellation based method of the same authors, time permitting. Explore what can be obtained with EMSegement of Slicer3. Compare and contrast all sets of results. Also, explore preliminary labeling.

Progress

Updated every day.