2009 Summer Project Week 4D Imaging
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Key Investigators
- BWH: Junichi Tokuda, Wendy Plesniak, Nobuhiko Hata
- WFU:Craig A. Hamilton
Objective
Implement a set of 3D Slicer modules to handle 4D images in 3D Slicer for perfusion analysis, cardiac, etc. including:
- Manipulation
- Loading 4D volume
- Scroll time-line
- Edit frames
- Processing
- Image registration for motion compensation
- Analysis
- Perfusion analysis: fitting pharmacokinetic model
Approach, Plan
- Loading 4D image. We will implement a feature that allows the user to load a series of 3D images from a specified director. The data can be either in DICOM or NRRD format.
- Time line. We will develop a scroll-bar interface to scroll the frame in time-direction. It allows you to scroll the frame for foreground and background screens independently to compare two images at the different time points.
- Motion compensation. We will develop a method to compensate organ motion (respiratory motion, cardiac motion etc.)
- Intensity plot. We will implement an interface to plot temporal changes of intensities at specified regions. This feature is useful for analyzing dynamic contrast images.
- Model fitting. The module provides a python interface to analyze intensity curves obtained from the 4D images. The interface will be used to fit pharmacokinetic models to intensity curves to obtain perfusion parameters.
Progress
