2010 Winter Project Week WM ATLAS

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  • Automatically segmented fiber tracts.

  • Example whole-brain tract cluster mean fibers.

Key Investigators

  • Lauren O'Donnell (Instructor, Harvard Medical School (BWH))
  • Carl-Fredrik Westin (Professor, Harvard Medical School (BWH) )
  • William Wells (Professor, Harvard Medical School (BWH) )
  • Alexandra J Golby (Professor of Neurosurgery, Harvard Medical School (BWH) )

Objective

Implement tract-based morphometry pipeline in 3D Slicer, including atlas-based WM (white matter) segmentation and whole-brain WM coordinate system generation. Investigate integration of FMRI+DTI into atlas pipeline, for neurosurgical planning applications.

Approach, Plan

The original pipeline consists of (over a group): --preprocessing

DTI and FA image calculation, congealing registration of FA images, whole-brain tract seeding, application of registration to tractography,

Progress

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