2011 Winter Project Week:DTIPrepDocumentation
Diffusion Weighted Imaging and Diffusion Tensor Imaging Quality Control_DTIPrep
3D view of gradients before and after Quality Control procedures
Motivations: Automated Diffusion Weighted Imaging Quality Control
Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. Unfortunately, the DWIs suffer from a lots of artifacts because of the inherent low SNR and long scanning time of multiple directional encoding. Thus, it necessitates the development of Quality Control (QC) as the automated tool for DWIs. We have developed a tool called DTIPrep which is fully open source. In the DTIPrep framework, the following checking procedures are applied within a pipelining structure and described by a protocoling file. These pipeline procedures include: 1) image info checking, 2) diffusion info checking, 3) Slice-wise intensity checking, 4) Interlace-wise intensity checking, 5) Averaging baselines, 6) Eddy-motion correction, 7) gradient-wise checking, 8) Computing DTI measurements and saving. As our current study, we are focusing on extending DTIPrep to detect artifacts through DTI data. According to our experiments, there are a number of artifacts which can not be detected from the DWIs using only voxel-wise knowledge. For example, residual artifact presence after DWI QC which shows a reddish appearance for DTIs.
Key Investigators
- UIowa: Hans Johnson, Mark Scully, Joy Matsui
- UNC: Martin Styner, Clement Vachet, Mahshid Farzinfar, Cheryl Dietrich
Objective
1. Introducing new automated QC tool called DTIPrep that includes the pipeline checking and correcting procedures against the DWI acquired protocol and generating QCed result.
2. Integrating the visual checking considering into the automated QC procedures consistently and synchronously.
3. Developing DTIPrep by introducing new measurement of DTIs properties to detect residual artifacts presence after DWI QC.
Approach, Plan
Update the NITRC media wiki pages for DTIPrep to match the current version of the program. Use the updated wiki as a basis for a tutorial. Coordinate efforts with Cheryl Dietrich at UNC.
Progress
A detailed pdf on DTIPrep documentation has been uploaded from UNC. Work has started on creating a NAMIC-style ppt tutorial and will be completed soon. This tutorial will be submitted for the June tutorial contest.
