DBP3:Utah:RegCases

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Background

• The CARMA Center uses late gadolinium enhanced MRI (LGE-MRI) images to evaluate new patients, predict procedural success, and evaluate therapeutic outcomes. The MRI images for each patient are further accompanied by MR angiographic images (MRA) and manual segmentations of relevant structures. These images are acquired longitudinally over the course of a patient's evaluation, treatment, and follow-up (i.e. months or years). Registration is often necessary to compare images from different time points in a patient's treatment, across patient cohorts at the same stage of disease progression or treatment, or different image types.

Pre-ablation LGE-MRI Image	Post-ablation LGE-MRI Image	Segmentation of LGE-MRI Image

MRA Image	Immediately Post-ablation (IPA) LGE-MRI Image

Implementation

• We need to define a suitable set of registration parameters for each of the above cases
• We will develop a Slicer extension module with the pre-defined registration parameters for each of the above scenarios