2012 Summer Project Week:DifficultRegistration

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Projects List

Registration Result Visualization

Slicer:BRAINS

NiftyReg

SIFT Landmark

Key Investigators

Erasmus Medical Center: Stefan Klein
University College London: Marc Modat
UNC: Aditya Gupta, Martin Styner
BWH: Matthew Toews, Petter Risholm, Dominik Meier, William Wells

Objective

To identify solutions to difficult image registration problems that challenge the limits of current technology. Aspects of difficulty will include:

inter-subject registration
truncation, missing tissue
unknown initialization
inter-species registration
articulated deformation

Approach, Plan

A set of difficult pair-wise registration problems will be considered. Participants will discuss workable solutions based on their expertise and background, and these solutions will be documented.
Registration cases can be found here.

CT: atlas and torso have flipped orientation: Correction Xforms here: Flip CT atlas&torso, zip file with 2 .tfm files

Progress

We held a general discussion of registration challenges in the community. Results were generated for head and neck data (Ivan Kolesov), three registration approaches were evaluated on challenging head and body images: (NiftyReg), (Slicer:BRAINS), (SIFT Landmarks).

Registration of difficult brain images is successful, body images remain challenging.
Registration direction has an important impact, i.e. which images are designed as fixed or moving. Symmetric or bi-directional registration is helpful.
Masking of problematic image regions, e.g. pathology, is an important but time-consuming pre-processing task that could be further investigated or automated. For instance, interactive masking/segmentation of pathology, linking registration and masking.

Delivery Mechanism

Attention Participants: Please log in and update/correct entries in the table below. For bonus points, please provide links or solutions to image registration problems on this page.

Participant	Affiliation	Context	Techniques	Solutions/Links
Steven Aylward	Kitware	CT, US, ressection, brain tumors, changing pathology, sliding organ	Sliding Geometry, Geometric Metamorphosis
Karl Diedrich	AZE	Rigid registration, abdomen	Multi-resolution registration
James Fishbaugh	SCI	Shape analysis and registration
Aditya Gupta	UNC	DTI, enlarged lateral ventricles
Stefan Klein	Erasmus Medical Center	General Registration
Ivan Kolesov	Georgia Tech	Articulated, point-based registration	Plastimatch, NiftyReg	Head Neck Results
Dominik Meier	BWH	General registration	Slicer: BRAINS	IntraOp: TBI: CT torso: FAILED
Marc Modat	UCL	neuro-deg. diseases, longitudinal	NiftiReg	Some test res
Albert Motillo	GE	Parsing CT, Detection
Simrin Nagpal	Queens University	CT/US registration
Samon Nuranian	UBC	US-guided intervension, spine
Andre Remi	UCLA	Longitudinal changes in TBI, tissue types
Peter Risholm	BWH	Brain, head and neck, radiation therapy	Probabilistic Uncertainty
Samira Sojoudi	UBC	Spine, CT/US registration
Matthew Toews	BWH	General registration	SIFT landmark correspondence	MR-brain: CT-torso:
Bo Wang	Utah	TBI image segmentation
Kevin Wang	Princess Margaret Hospital	Adaptive radiation therapy, longitudinal
William Wells	BWH	Interventional applications	Theory: Segmentation, Registration