Distribution modeling
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Key Investigators
Anuja Sharma, Guido Gerig
Project Description
Objective
- Model probability distributions along DTI fiber tracts instead of scalar summary measurements to create a tract profile (e.g. cross-sectional averages).
- Our spatiotemporal modeling method utilizes these distribution-valued data to create growth trajectories such that the complete probability distribution is estimated continuously in space and time.
- Create a spatiotemporal growth trajectory for the healthy infant population. Evaluate our method's ability to detect clinical differences in infants with Krabbe's disease when compared with the control population.