2014 Summer Project Week:Tumor Heterogeneity Analysis

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  Projects List

Key Investigators

• Vivek Narayan
• Jayender Jagadeesan

Project Description

HeterogeneityCAD module for Slicer (openCAD Extension): Quantify the heterogeneity of Breast tumors and their parameter maps through several classes of metrics.

Objective

• Create a Slicer module to analyze a segmented tumor and its parameters maps (i.e. k-trans values from DCE-MRI).
• Implement known metrics to extract feature data
• Draft a framework to export, visualize, and compare information among cases

Approach, Plan

• Design a Slicer module using python and numpy
• Research and implement various classes of metrics and features: i.e., first-order statistics, morphology/shape, fractal dimensions, geometrical measures, texture-based features

Progress

• Implementing geometric measures and features derived from texture matrices, while researching new metrics.

References

• http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Extensions/OpenCAD