Inter-slice Motion Correction for fMRI
From NAMIC Wiki
Home < Inter-slice Motion Correction for fMRI
Contents
Objective
* To perform inter-slice motion correction in fMR images using affine and non-rigid registration methods.
Progress
* Implemented and tested b-Spline/affine registration with Wells-MI and KL metrics.
Results
Affine
- affine motion with all metrics degrades the inter-slice registration.
Open questions
* Intensity normalization / histogram equalization - would these have any impact on inter-slice registration? Would they affect the computation of the joint-entropies for MI/KL metrics. * Should there be some regularization factor on the registration to limit the motion ?
To Do
* Right now, registration is done on a slice by slice basis. However, due to the low resolution of fMRI and the absence of gradients result in low registration accuracy. We are investigating using alternative image-to-image metrics like the KL divergence. We are also looking at simultaneously registering multiple slices.
Key Investigators
* Firdaus Janoos, Raghu Machiraju, Steve Pieper, Wendy Plesniak.