2008 Winter Project Week:Resampling DTIs with Slicer3

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Key Investigators

• BWH: Francois Budin, Sylvain Bouix

Objective

The goal of this project is to develop a command line module for slicer 3 to resample DT images. This module will be compatible with several ITK 3D transforms (rigid, affine and non-rigid) and implements different diffusion tensor interpolations.

Approach, Plan

Our approach is to build the ITK infrastructure (ITK diffusion tensor interpolators and ITK diffusion tensor transforms) to support this module. Our main purpose at the Project Week is to implement a non-rigid transform for diffusion tensor images.

Progress

The module currently supports:

• Several blockwise diffusion tensor interpolations
  • Nearest Neighborhood
  • Linear
  • BSpline
• Some Transforms
  • Rigid3D
  • Affine - Finite Strain
  • Affine - Preservation of Principal Direction

To implement:

• non-rigid transforms
• better interpolations

References

• D.C. Alexander, C. Pierpaoli, P.J. Basser, J.C. Gee. Spatial Transformations of Diffusion Tensor Magnetic Resonance Images, IEEE Transactions on medical imaging, vol. 20, No. 11, November 2001