NANOMA-collaboration

Overview

The objective of this work is to develop a novel drug delivery system for breast cancer treatment under Magnetic Resonance Imaging and Navigation. The idea is to exploit the use of magnetic gradient fields in the MR scanner to propel and track the drug coated nano particles simultaneously.

Team

This is a collaborative project involving investigators based in the US and Europe. The expertise of the team includes design and fabrication of nano/micromechanical systems, image processing, navigation algorithms, robotics, modeling and control of smart systems and MR physics. The team comprises of:

• Constantinos Mavroidis (Northeastern University, USA)
• Antoine Ferreira (Ecole Nationale Supérieure d'Ingénieurs, France)
• Christian Dahmen (Carl v. Ossietzky University, Germany)
• Noby Hata (Brigham and Women's Hospital, Harvard Medical School, USA)
• Jayender Jagadeesan (Brigham and Women's Hospital, Harvard Medical School, USA)
• Panagiotis Vartholomeos (National Technical University of Athens, Greece)

Events

• Teleconference call on January 08, 2009 involving Dinos, Noby, Antoine, Jay and Tim (for Christian) to discuss the short term and long term goals of the project as well as the future course of action.
• Personal meeting on January 30, 2009, in Boston, MA, USA. Participants: Jay, Dinos, Christian and Tim. Discussions about the prospects of joint applications to different open calls. Planning of joint experiments in Boston.

Support

This work is being supported by the following grants:

• European Consortium Grant (number: ...)
• ...
• ...

It is planned to apply for the following grants:

• NSF PIRE (deadline February 26, 2009)

Additionally applications to the following may be useful:

• FP7-PEOPLE-2009-IRSES (deadline March 27, 2009)
• NIH R01 (deadline June 1, 2009)
• possibly EU HEALTH

Progress

• The initial plan of action is being formalized.

Resources

• Siemens Verio 3T MRI scanner (BWH).
• GE Signa 3T MRI scanner at BWH.
• GE Signa 1.5T MRI scanner at BWH.
• Slicer

Archive

• PDF Documents related to magnetic nanoparticle drug delivery systems:

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