2009 Summer Project Week Multimodal SPL Brain Atlas

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Key Investigators

• BWH: Ion-Florin Talos, Michael Halle, Wendy Plesniak
• GE: Jim Miller

Objective

To explore ways of linking the image data of the SPL multi-modal brain atlas (label maps, 3D-models) with ontological information on brain morphology and function

Approach, Plan

• continue work on XML-based intermediate data representation that supports anatomical hierarchies and can describe arbitrary overlapping image regions (e.g. brain functional systems)
• application integration of the new XML-based data representation (3D-Slicer)

References

1. Talos IF, Rubin DL, Halle M, Musen MA, Kikinis R. A prototype symbolic model of canonical functional neuroanatomy of the motor system. J Biomed Inform. 2008 Apr;41(2):251-263. PMID: 18164666. PMCID: PMC2376098. 2. Rubin DL, Talos IF, Halle M, Musen MA, Kikinis R. Computational neuroanatomy: ontology-based representation of neural components and connectivity. BMC Bioinformatics 2009; 10(Suppl 2):S3. PMID: 19208191. PMCID: PMC2646240.